Classical Pathway of Complement System

[SuperTalvar]

Should be called the complicated system

[soojinlee]

I got through Pre Med because of you. Sometimes your lectures were too advanced for me and I thought "I will probably need these when I'm in medical school." 5 years later and I will get through medical school because of you. Thanks man. I hope someone is paying you very well out there.

[gggggggggg-ucss]

Fragment b is always kept and Fragment a is thrown into the plasma, but there is one exception, it's for C2. So instead of keeping C2b, you keep C2a instead.

[nooshinmirzaee]

i love the way you stress on words it helps me stay focused.. ;)
you are born a teacher, keep up the good work

[midnightsblaze]

In respect to the C4bC2b complex, for about 5 years or so in the recent past, immunology textbook writers wanted to make the process more uniform since C2a is the only large factor which remains associated with the cell surface and renamed it C2b to be more inline with C4b. So C4bC2b was published for a couple of years but it never really stuck as C4bC2a was already widely accepted and established.

[aslanr]

clearest explanations on youtube. Much better than a certain "academy"

[neslihangroll]

You helped me to pass the oral exam in Biochemistry in Step1. My professor asked me the questions you underlined in your videos and it would normally required me to read thick text books to understand. Now you are helping me to pass Immunology. I can't thank you enough.

[Arthensolutions]

Hi! I'm from Brazil, I'm Pharmacy student, and I must say u r an incredible teacher! Your classes help me a lot! Thanks for Everything!

[leonidas]

This was SO helpful - You are making such a difference for me. I am almost crying of hapiness

[ronettechojnacki]

Thank you. You saved my life today!! I needed to teach the Complement System to my students and this explained it so well. THANK YOU!!!!

[mssxiyf]

you made me understand in less than 15 minutes what my professor couldn't make me understand in more than 2 hours. thanks a lot :)

[codyrussell]

I just want to say ive watched this guys videos since grad school immunology. I am now in medical school, and still use his videos on all go his topics. 10/10 would reccomend AK Lectures!!

[edessatanafranca]

Hi I noticed that the C3 convertase should be C4bC2a ☺️ I looked it up in Immunology 7th Ed David Male page 90 fig. 4.4 ☺️

[htetlin]

Hello AK lecture, according to my professor, C4bC2a is the C3 convertase that cleaves C3 to C3a and C3b. And also C4bC2aC3b is the C5 convertase and C3 convertase cannot cleave C5. Please keep on making video. thank you very much.

[sonamraghav]

love your accent 😍😍😍, the way you speak 😘😘 understandable

[lujainaa]

He’s so good at explaining. I can’t do this even if I have perfect understanding of something.

[ameeralbaghdadi]

You are the best and i guess the only one on youtube who really deeply understand the scientific material and introduce it with no side talk and in a very simple and informative method
Best regards to your efforts

[bkjrkwu]

I love u man u are the best lecturer i have seen ❤️❤️❤️❤️❤️

[buixuanbaodanh]

Your lectures are amazingly easy to understand. I'm so grateful for your effort.

[apricotpomegranate]

I like how you started with the big picture first and then went into the nitty gritty details. My immunology prof doesn't do that enough, hence why I'm here. She will drill the process steps, but doesn't really get at the purpose of why these things happen. Thanks for this. :)