Alpha Adrenergic Receptors: Alpha-1 & Alpha-2

In this 2021 NEI Congress Highlight, Dr. Jeffrey Strawn reviews the classification and distribution of alpha adrenergic receptors.

There are 2 main types of alpha adrenergic receptors: alpha-1 and alpha-2. Both alpha-1 and alpha-2 adrenoceptors have numerous subtypes that are distributed differently across a number of regions throughout the body. Alpha adrenergic receptor agents, including alpha-2 agonists (such as clonidine or guanfacine), or alpha-1 antagonists (such as prazosin), may exhibit different therapeutic effects and tolerability profiles based on their selectivity for alpha-1 and alpha-2 adrenoceptors, and their respective subtypes. Agents acting on these receptors result in a variety of actions depending on the type as well as the location in various organs and tissues.

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[StoicScape]

Working on my APRN studies 👍🏾 Thanks for this

[dirtdog]

Alpha-1 subtypes are actually A, B, D!!