Sickle Cell Disease by V. Tran, N. Archer | OPENPediatrics

By the end of this video, the learner will be able to describe the fundamental elements of sickle cell disease, including pathophysiology, potential complications, and management strategies.
0:00 Introduction
3:18 Pathophysiology
5:06 Complications
9:13 Management
15:13 Summary

LEARNING OBJECTIVES
By the end of this video, the learner will be able to:
• Describe the fundamental elements of sickle cell disease
• Discuss the pathophysiology of sickle cell disease
• Identify the common complications seen in this condition
• Describe the management options for sickle cell disease and its complications

AUTHORS
Virginia Tran, BS
Harvard Medical School

Natasha Archer, MD
Physician
Dana Farber/Boston Children's Cancer and Blood Disorders Center
Assistant Professor of Pediatrics
Harvard Medical School

DATES
Initial publication: June 9, 2023


OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access and thus at no expense to the user.


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CITATION

[teanikahoffman]

Please stop telling providers the genotype HbSC is “ milder” by the time a person reaches adulthood it all becomes severe

[Rene-uzeb]

6:45 a higher calcium diet in rats delayed hypertrophy. Bp medication made it worse.
Careful though: large intake will result in more urinary calcium, effected by calcitonin, and the precalcitonin levels are used to diagnose serious infections. So calcium intake right before a blood test should be avoided

[Praise_ye_Yahweh]

I find the video very helpful, but the mutation occurs on the 11th chromosome, not the 6th chromosome.