Sickle Cell Disease | Pathophysiology, Symptoms and Treatment

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Lesson on sickle cell disease. Sickle cell disease is a group of heritable blood disorders with characteristic sickle-cell shaped red blood cells. Sickle cell disease leads to chronic, compensated hemolytic anemia with vaso-occlusion from sickling of red blood cells.

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JJ

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*

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JJ
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USMLE tip: HB A1c is not always reliable in monitoring glycemic control in patients with hemoglobinopathies & SCD

ahmedahm
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I love your presentation and the way you explain the lecture, many thanks ! 🤩🥰

r.y
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Thank you so much! your lectures are excellent!! do you recommend any textbooks in particular? I'm reading Hoffbrands essential hematology, but it's quite detailed

patriciadesouzapimenta
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MY MOM HAD SICKLE CELL AND COOLEY’S ANEMIA! HER OLDER SISTER(MY AUNT) HAD ONLY SCD-NON -COOLEY’S ANEMIA. MY AUNT DIED FROM COMPLICATIONS DUE TO ACUTE PANCREATITIS AT THE AGE OF 65. MY MOM RECENTLY DIED FROM COMPLICATIONS DUE TO ACUTE LIVER FAILURE…I’M SURE THOSE LITTLE DEVILS FOUND THEIR WAY INTO HER LIVER. HER POOR LIVER DIDN’T KNOW WHAT TO DO…SO IT SHUT DOWN. SHE DIED BACK IN LATE MARCH OF THIS YEAR! SHE WAS 14 MONTHS SHY OF HER 80TH BIRTHDAY! MY BROTHER AND I HAVE THE TRAIT AS WELL AS G6PD DEFICIENCY! MY QUESTION IS, HOW DO YOU TEST FOR COOLEY’S ANEMIA TRAIT?

OnlyGamesPlayed
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The video's very helpful. Thank you 🙇

rashidabalaabdullahi
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What about aplastic crisis, ???? B 19 virus

victormanuelmbisbee
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pittbrad