The Purdue Lecture Hall Series - Sneha Subramanian, Biological Sciences, Purdue University

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Welcome to The Lecture Hall Series, now in its sixth year, where we proudly showcase talks delivered by Purdue graduate students. Join our host, Dr. Tommy Sors, Director of Scientific Strategy and Relations at the esteemed Purdue Institute of Inflammation, Immunology, and Infectious Disease, as he presents engaging discussions that unveil the fascinating journeys of these budding researchers. Each graduate student speaker provides an insightful glimpse into their personal path into scientific research, along with the exhilarating experiences they encounter in their pursuit of advanced degrees. This program has garnered widespread popularity, particularly among high school teachers who utilize these videos to illuminate modern scientific approaches and the exciting avenues for careers in the world of science. Both high school and undergraduate students gain a firsthand exposure to the remarkable research transpiring at Purdue. For our graduate student lecturers, this platform offers a unique opportunity to engage a diverse and non-technical audience, enabling them to convey the exhilaration of scientific discovery. As we continue to grow, we eagerly seek new student lecturers, and we warmly welcome faculty involvement in encouraging participation.

Sneha Subramanian, a dedicated PhD candidate within Purdue University's Biological Sciences Department, is making significant strides in cancer research under the guidance of Dr. Claudio Aguilar at the Purdue Institute for Cancer Research. Her illuminating discussion recounts her profound journey through the realm of scientific exploration, crediting her mentors for igniting her curiosity and nurturing her passion for biological sciences. With a broad focus on crafting novel and highly selective targeting agents for cancer, Sneha employs innovative strategies rooted in endocytosis modulation. Her comprehensive approach integrates an array of cutting-edge cell, molecular biology, and biochemical techniques. Central to her discourse is EGFRvIII, an oncogenic variant of Epidermal Growth Factor Receptor. By uncovering its distinctive role in the formation of intracellular compartments, Sneha sheds light on how EGFRvIII reshapes physiological dynamics. This pioneering work lays a vital foundation for novel cancer therapies, promising advancements in the relentless pursuit of curative interventions.

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