The Convergence of CRISPR and Human Stem Cells

Gladstone President Deepak Srivastava moderated a conversation with Jennifer Doudna and Shinya Yamanaka to discuss the potential impact of CRISPR and iPS cells over the coming decade and hear from the two world-class scientists about how they plan to shape the enormous opportunities that lie ahead.
Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012 for his discovery of induced pluripotent stem cells (iPS cells). And last year, Doudna received the Nobel Prize in Chemistry for her co-discovery of the CRISPR-Cas9 gene-editing technology. Arguably the two most impactful advances of this century, the discoveries by these Gladstone investigators are now accelerating our understanding and treatment of human disease at an unprecedented pace.

#stemcells #stemcellresearch #crisprresearch

[kevinjimoh]

Crazy. Crazy crazy crazy.

Thank you guys for having this talk and making it accessible to me. It means more than you know

[tiantina]

As a biochemical graduate now working in a completely different industry, the information shared in this conversation is still inspiring. It kinda made me want to go back into the "boring" research lab routine and reset my entire career life!

[lifeeasier]

Such a privilege to have this available. What are the current successful applications of both technologies?

[eternalambition]

Thank you So much for this talk...the meeting of 3 great individuals in one talk...miraculous!!!

[lilysunshine]

Humans working to their full potential.

[melissabracken]

Stem cells expanded from umbilical cords that are normally thrown away shouldn't pose an issue.

I feel like the pharmaceutical industry is the reason we are being held back from therapies that are being practiced on a regular basis in other countries.

I just got back from receiving stem cell therapy through an IV on three separate days and had two grams of placental implants injected into my abdomen. All these treatments, including the over 150, 000, 000 stem cells, cost less than $3, 000 US dollars in Guadalajara! I also received stem cells expanded from the pulp of children's teeth, peptides, and exosomes, as well. These fresh stem cells were nearly 100% viable. They were not cryogenically frozen beforehand and thawed.

Why isn't this the norm in the US? Why does the pharmaceutical industry have so much power over here?

[metipallearuna]

Like creating some mis-sense that nobody would've seen it in an Ant moving on the pair of false walking legs without any lab facilities like crispr cas9 editing.