Special Senses | The Phototransduction Cascade

Ninja Nerds!

During this lecture Professor Zach Murphy will be teaching you about the photo transduction cascade. We go into great detail on how the images we see eventually reach the retina where it is then transmitted by photoreceptors including the cones and rods, which respond to different types of light. Finally, these impulses are carried by ganglion cells which form the axons of the optic nerve. We hope you enjoy this lecture and be sure to support us below!

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[HappyLife]

Six years later and it is still the best on the internet.

[ManirBuhariAbbakarAssada]

THE WAY YOU BREAK DOWN ALL THESE COMPLEX ANATOMICAL STRUCTURES INTO SIMPLER FORMS TO FERCILITATE EASY UNDERSTANDING ... ... ... IT'S TRULY AMAZING !!!

[lividcoffee]

You are literally better than all of the professors in my University

[Minnie.__.]

I can't believe I just watched this 42 minute lecture and was engaged the whole time. You are such a great teacher. Thank you so much!

[danielbleykhman]

This is extremely enlightening. I can't believe it took me until Neuro to finally watch this (already took Histo, Physio, and Biochem and no professor could make this clear for me).

[erikmortensen]

Hey man, great content! I did find this particular video somewhat lacking on the topic of ON/OFF bipolar cells (in respect to cones) as well as center/surround field ganglion cells. I think this is a central topic to tackling peripheral visual processing and should at least be mentioned if not explained in detail

[nadimsheikh]

Never heard a better teaching tutorial - fantastic, crystal clear or as we call in Urdu "Sheesha"

[rileswain]

Taking an intro to neuroscience course and this answered every one of my questions. Thank you so much! Somehow my textbook forgot to mention "why" and "what" happens after the photoreceptors become hyperpolarized. Confused the hell out of me. Now it makes so much sense thanks to your video. Keep up the good work! I look forward to watching your other videos!

[burhanco]

Possibly the best video out there that explain vision physiology and phototransduction in particular. Very thorough and virtually a whole chapter in a video. More power!

[Susamammut]

you always save me before every single exam- thank you so much for all the effort you are putting into your lectures!!!

[Dr-AI]

I really enjoyed your joke about the cells not being bi-polar

[justjayden]

You are a well “versed” educator, and incorporate a lot of really useful techniques to make the information absorb easy peasy!

[subashchandrabowse]

Amazed at his fluency and knowledge on Transduction cascading..

[edita]

Thank you a million times! Finally, I understood! Trying to learn from my textbook and watching the material provided by the instructor is like walking in the dark tunnel and seeing no light. Just got overwhelmed with all those words on the pages and pages of information, and having no clue what they are trying to tell me. Finally, I get it!! Your videos are a blessing, especially for the ones that study from home and try to make sense of the whole small details in a&p!

[shuraymsudaysi]

Am medical student from Somalia
And this video and all ur videos helped me alot. am very grateful for u, thanks Dr ninja.
Keep going

[menatollasoliman]

As an optometry student, we thank you GREATLY. Incredible, in depth, yet precise. Thank you so so much for this!

[Psilt]

i like your videos, but i think in this one you missed some stuff... like differentiation between on and off cells and i think for the sake of understanding it would be better to say that rods/cones usually inhibit bipolar cells (with large amount of neurotransmitter) and when light inhibits them, it allows for signal to be transmitted (rather than to say that small amount of neurotransmitter excites the post-synaptic cell).
Basically when the thing that inhibits something gets inhibited, the something can create APs. (A - light) --I (B - rods) --I (C-bipolar) = (A) --> (C) --I is inhibition, --> is stimulation

Also, it's worth mentioning that horizontal cells and amacrine cells create the lateral inhibition (inhibit light transmission to neurons close to the neuron being stimulated) which improves resolution/acuity

keep on trucking!

[victoriafarasat]

I hope you know how much we all love and appreacite everything that you do. You truly are the ost amazing person on the planet

[yenismarcabrera]

From the bottom of my heart, God bless you! Thank you for helping me understand what I've been trying to make sense of throughout a whole semester at optometry school lol this and other videos. All your videos from ALL the subjects ROCK!

[tejasvisakhamuri]

36:28 - The Recap
Thank you so much, watching your neurology series, and they’re really helpful.