Genes that Regulate Sleep and Circadian Rhythms – Lecture by Nobel Laureate Michael Young

In December 2018, Nobel Laureate Michael Young gave a lecture to students and young scientists at the University of Science and Technology in China on the topic of “Genes that Regulate Sleep and Circadian Rhythms”. He described his reseach into circadian rhythms and his journey towards receiving the Nobel Prize in Physiology or Medicine in 2017.

This lecture was part of the Nobel Prize Inspiration Initiative (NPII), a global programme designed to help Nobel Laureates share their inspirational stories and insights. By taking Nobel Laureates on visits to universities and research centres around the world, and by capturing their thoughts on video, the Initiative seeks to bring the Laureates into closer contact with the worldwide scientific community, and especially with an audience of young scientists. NPII China 2018 was delivered in partnership with AstraZeneca.

[UrduPost-fv]

such a wonderful work. beautifully explained. i am amazed be the fluency and complete grip on research. these are the scientist who actually gives a base or starter for further or big researches. unfortunately, whole world lacks the appreciation and recognition of such gems.

[michaelshannon]

Delayed Sleep Phase Disorder, try explain this one to other people. They just dont get it. We are still ways behind in understanding ppl with rare, exceptional issues.

[fuzzy-life]

Such great talks seem to have one thing in common, they start with an accidental discovery and later they decide to devote their lives to study it. so many thanks for enlightening the rest of US :) One thing i am wondering though is that relating sleep disorder to short life span may be not be right given that there may be other genetic confounders like shortening of telomeres or some epigenetic mechanisms of just environmental factor like moving away from tropics?

[tiechen]

I joined The Rockefeller University at the end of 1994 as a postdoc to study vaccine development under the supervision of Emil Gotschlich, the pioneer in creating a vaccine against bacterial meningitis. Every Friday afternoon at 3:30 pm, there was a series of scientific talks, usually presented by prominent scientists. Although my boss insisted that every department member should attend, I felt somewhat compelled. The first scientist I heard in this series was Michael Young. However, his talk was uninteresting, focused solely on conceptual ideas. In my view, medical sciences should be practical and contribute to the university's mission: "Science for the benefit of humanity." I couldn't comprehend how studying the biological Time Bell aligned with this mission. Consequently, I concluded that Rockefeller University wouldn't receive any more Nobel Prizes. However, since my departure from the university at the end of 1999, faculty members from Rockefeller have won at least seven Nobel Prizes.

[chrisjanegriffinking]

Brilliant lecture. Do plants feel pain. Do bees feel pain?

[polina]

I don't quite understand: if proteins are degraded in cell when affected with light, how does this oscillation mechanism worked for the rodent placed in a dark environment?

[ItzNim]

Is there an age that this gene gets turned on? I have had delayed sleep all my life even when I was a baby. I assume it is just who you are at birth? Personally this gene variant has made my life frustrating. I consistently have issues with staying up late into the morning, being too tired or "oversleeping". I just bought a sleep clock today to see if that helps

[endgamefond]

Can i get the lecture notes or paper of this lecture?

[tonynewman]

Were these test done in a Faraday ( Concrete iron building) cage ? What if any would 5G effects noted?

[GeorgeBakalovPRO]

So these Chinese students actually understand English at this level? If they indeed do, that’s very impressive!