Old Penicillin vs Germs Under Microscope

[teeheebutts]

Here are a couple reasons why this didn't work:

1. Penicillin works by preventing the final piece of peptidoglycan cell wall from clicking in to place, so cell death only occurs if bacteria tries to replicate, damages their own cell wall, or just gets too old.

2. Penicillin V is not terribly water soluble and needs a nice soak in stomach acid to be bioavailable in vivo.

3. Most of your bacteria here look like gram negative rods and a few spore-forming gram positive rods (most likely Bacillus spp. or Clostridium spp.) which are likely to carry some penicillin resistance.

4. You shouldn't have ANY leftover antibiotics, young man! They NEED full courses to work! Don't make me go on my antibiotic resistance rant, it is endless.

Dope video though!

[heidelfortuny]

*adds penicillin*
bacteria: "this shi weak af."

*adds alcohol*
bacteria: 💀💀💀

[keintabak]

The message here is always drink isopropyl alcohol instead of taking antibiotics. Thank you Doctor for clearing this up 👍🏻.

[ZenfulHaze]

Got it; drink alcohol when you’re sick.

[meghanwillson]

And that’s why you have to take a FULL COURSE of antibiotics and not just stop after a few days when your feeling better. It’s to make sure the bacteria is aniahlated or you risk antibiotic resistant bacteria.

[Gigatony]

The lesson here is: stop using pills, just drink alcohol.

[thegamerwithin]

Two things here:
1. Simply dissolving pencillin won't release the active form. Since it's an oral formulation, it must go through stomach to become active. So, a solution of penicillin won't be effective against bacteria

2. None of our cell has cell wall. Bacterial cell wall has peptidoglycan. Penicillin disrupts synthesis of this chemical. Now fungal cell wall lacks peptidoglycan hence antibiotics aren't very effective against them

[crisantotajon]

Its not ineffective, its just that Penicillin only acts with bacterias sensitive to it. Thats why doctors prescribe certain antiobiotics depends on a specific desease.

[alto]

The penicillin in pills is not per say penicillin. It’s an analogue that needs to pass through the stomach acids and then be activated by cytochromes in the liver to be active

[karensimons]

I would like to see you treat mouth germs with salt water. Grew up with mother who was always urging gargling with salt water for many problems.

[AlexanderTzalumen]

The takeaway:
Don't drink dirty pond water
And
Don't follow it up with expired penicillin and expect that to treat your dysentery.

[DoomFinger]

Every bacteria is gangster until the isopropyl alcohol appears

[LeoA]

"I felt a great disturbance in the Force, as if millions of voices suddenly cried out in terror and were suddenly silenced."

[Kammerliteratur]

CORRECTION: it only affects the BACTERIAL cell wall, and only when the bacteria is growing

[wk]

Nice way to learn how medicine works.
Would be interested in seeing what a sneeze/mucus looks like, and maybe add some sort of disinfectant (bleach/lysol/peroxide, etc)

[JohnAustin]

The penicillin would have a lethal affect on me

[emachimia]

Penicillin works against the peptidoglycan cell wall in gram positive bacteria. Gram negative bacteria are generally not affected, as their peptidoglycan cell wall is protected by a lipidic membrane. This could explain why your bacteria have not been affected.
By the way: mammals, including humans, do not have cell walls, their cells do not have peptidoglycan and are not affected by penicillin. Penicillin affects the good bacteria in the intestine, and this is the main reason why you may get side effects like diarrhea. Penicillin may damage the bacteria that contribute to digestion.
I am not sure if simply dissolving a penicillin pill in water is enough.

[urbyfont]

Day 6 of asking to show sperm under the microscope?

[chrisdowdy]

Well here is the deal. Penicillin only works on very specific bacteria. You appear to have rod shaped bacteria which is often something like Bacillus that are in spore form. In addition, penicillin also degrades in efficacy over time. But its doubtful it worked because you gave it to spore formers.

I am a microbiologist.

[albrigsy]

You need only take a college course of microbiology to learn about different bacteria and different antibiotics. This is why you are prescribed certain antibiotics depending on your symptoms and also why it is so important to be honest with your Dr about that because different antibiotics work depending on what bacteria you are infected with. That's also why there are "broad spectrum" antibiotics because they will kill any and all bacteria including the natural flora, or natural bacteria that your body creates.