FiO2 PEEP Table | Medvarsity

At the start of mechanical ventilation, the most important priority is to provide effective oxygenation. To ensure the patient's safety following intubation, the FIO2 should always be set to 100% until adequate arterial oxygenation is documented.

A brief period with a FIO2 of 100 percent is not harmful to the patient receiving mechanical ventilation and provides several advantages to the clinician. Positive End-Expiratory Pressure (PEEP) is used to prevent the end-expiratory collapse of diseased pulmonary areas in order to reverse severe hypoxemia caused by pulmonary shunting, which is a defining feature of Acute Respiratory Distress Syndrome (ARDS).

Trans-pulmonary pressures of around 10 cm H2O are sufficient to keep the lung open at end-expiration in the presence of a normal surfactant. If the surfactant's tensioactive properties are compromised, trans-pulmonary bronchioloalveolar opening pressures can reach 25 cm H2O.

Dr. Raymond Dominic Savio, emphasizes on everything you need to know about initial fraction of inspired oxygen (FiO2), and positive End-Expiratory Pressure (PEEP) with FiO2 PEEP table, high vs low PEEP.