Lock and Key model

Enzymology | Lock and key model

The lock and key model is one of the earliest model proposed for the mechanism of enzyme action. It was proposed based on the fact that the enzymes are very specific for their substrates. This is just like keys are specific for their locks. According to this model, the active site of enzyme has same conformation as that of the substrate. This allows binding of the substrate in the active site of the enzyme, just like a key fits in lock. The enzyme then acts on the substrate and convert it into a product. One of The major drawback of this proposal is that it fails to explain the transition state that occurs when enzyme binds with its substrate

[khadijatulkubra]

Enzyme act as key while substrate as lock this is true concept

[sabhyaprajapati]

Thank🙏💕 you show much very easy explain

[ahcenemallem]

Thank you very much for this video, but I want more details about how to change the structure of the enzyme in the active site in the Kochland model induced fit . I mean how to change the sites of the acids amino to obtain a three-dimensional structure for structural integration with the substrate material. I searched, but I did not find sources on the internet.

[raniatariq]

i can hear 4 accents in ur voice



amazing

[sabhyaprajapati]

Sir molecular biology pr Easley videos banaye