Acetylcholine. ACh

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This video tutorial discusses the Acetylcholine also known as ACh.
0:00​. Intro to ACh
0:21​. What is ACh?
0:41​. What neurons release ACh?
1:47​. Synthesis of ACh
- 3:05. Hemicholinium
3:31​. Storage of ACh
- 5:07. Vesamicol
5:35​. Release of ACh
- 6:33. Lambert-Eaton Myasthenic Syndrome (LEMS)
- 7:01. Botulinum Toxin (Botulism; Botox)
8:59​. Cholinergic receptors (Nicotinic and Muscarinic)
11:48​. Inactivation of ACh
- 13:07. AChE Inhibitors (Organophosphates, Sarin gas)
13:43​. In-a-Nutshell
13:49​. Acknowledgements

[edwardyun]

I had a hard time understanding the process of synthesis and metabolism but this guy saved my life. Clear, easy and fun. Best educational video. Please stay in the educational field. Also, gentle people? you're amazing.

[Rockerfeller]

The GOAT of all medical related ACh videos

[adivasi]

my mind is blown. As a student from India I thank you for explaining these concepts so elegantly. Our current education system is corrupted as the intent is not about understanding but memorizing large words due to the pressure of scoring grades. We have so much to learn from how the way you teach

[ayahfattal]

Thank you sir, you have made Pharmacology much more easier and understandable. I watched your videos before an exam and i got You're GREAT

[lifeonthemoon]

You are the definition of a high quality teacher. I hope to be able to teach students the way you do. Please never stop making videos you’re a blessing. Currently a resident doctor in the UK and these videos are helping me with my training.🙏🏽🙏🏽🙏🏽

[jome]

What a teacher! the best so far. made it very simple and objective. congrats!

[manaswinisahoo]

Very beautifully explained and demonstrated. Just love it.
- a Veterinary Student from India.

[byamukamahamson]

Am a student from Uganda, I like uo presentation, they are soo touching and easily understandable

[rapstartwagi]

Mr Handy Anatomist, your lectures are enjoyable and you make them easy to understand, thanks

[KerryKarl]

This simplified this concept so well! I’m glad I found this video. Great job teaching!

[ahmedwaly]

a 2 hour lecture is explanied in14 mins thx a lot doc

[Darkklordd]

He's back!!!! We've missed you! Hope you and your loved ones are safe! Will always cheer for your amazing work!

[kavinthegreat]

This one video taught me more than a 2-hour lecture about ACh.

[saranawzad]

Wow, you summarized three lecture for me, amazing. I don’t believe it.

[pharmacyaspirant]

Best video abt cholinergic avlbl on yt 👍👌👌

[docsampencilstrokes]

oh you just ease me of my stress, thank you so much and God bless you

[Thekraziesars]

voice is very similar to Sal Khan, I thought it was him for a sec haha. Thank you Dr. Morton for your videos. Helps a lot.

[RakeshKumar-dszj]

This video has made my concept crystal clear. thanks!

[mariociencia]

Amazing! Fantastic! Incredible! Astonishing! Mighty! Better than most of Marvel's superhero movies!

[Paul-huht]

This is so crucial for people with MTHFR / Methylation issues (which are often downplayed as "quackery") because without proper synthesis of choline from phosphatidylcholine, there will always be a lack of choline to support ACh synthesis. I have C677T ++ but also an impaired PEMT gene, and whilst MTHFR led me down a path of "Methylfolate is everything" I came to realise that Choline support is huge - especially in my case. So it would appear for me that taking Alpha GPC would bypass the impaired PEMT gene and better support my ACh synthesis, as choline supplements apparently do not cross the BBB as well and phosphatidylcholine requires synthesis (via PEMT) so that's also a no-go (stuck coins in your gumball machine - or rather, lack of coins to begin with! 🤣) I've only been studying this for 8 months with no medical/scientific background, but have so far "cured" my migraines (not 1 after suffering daily for 20yrs) and am now focusing on ADD/ADHD. Great video.