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Can Fasting Make You Happier?
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___________________
DR. MINDY'S NOTES:
1. What is chemically happening to us when we feel happy?
- Dopamine - happiness, pleasure, reward centers, sleep, memory, impulse control
- Dopamine is made in our brain (substantia nigra) & sent to our hippocampus (receptor sites)
2. What causes our brains to release dopamine?
-pleasurable activities
-food, sex, drugs
-social media, texts, etc.
3. Can we become addicted to dopamine? YES
4.Can we become intolerant to dopamine? YES
5. Do we need more dopamine releasing activities to feel the same effect? YES
6. Can we reset our dopamine pathways so we feel more happiness with less dopamine? YES
7. How do we do that?
LET’S TURN TO SCIENCE:
OBESITY & AGING:
-hypothesized that diminished dopaminergic neurotransmission in obesity may promote excessive food intake as a means to compensate for reduced sensitivity to reward (1).
-insulin & leptin resistance contribute to diminished dopamine signaling from midbrain
-obese patients were shown to have less D2 receptor sites to receive dopamine
FASTING RESEARCH:
-increased D2 receptors in rats
24HR FAST:
”Fasting caused a change in the properties of somatodendritic dopamine release, possibly by increasing dopamine release, and that this increased release can be sustained under conditions where dopamine neurons are highly active”
OTHER NEUROTRANSMITTERS;
Increase BDNF- improve dopamine signaling in hippocampus
Increase serotonin- precursor to oxytocin & melatonin, regulates moods, feelings of well being, helps you relax, sleeping, eating, and digestion.
Dopamine & serotonin have an inverse relationship.
-when dopamine goes up on a regular basis, your serotonin levels fall.
-when serotonin falls so does melatonin
8. Where are these two neurotransmitters made?
Dopamine- Substantia Nigra (brain)
Serotonin-90% in your gut (gut)
9. Where are the receptors for these two neurotransmitters?
Dopamine - 5 different types: Hippocampus, peripheral tissues including kidneys
Serotonin -15 different types of receptors: gut, nervous tissue (brainstem), skin, tastebuds
10. Can you become dopamine resistant?
Dopamine tolerance
-addicts know this, you need more dopamine to get the same high
-tolerance is the place where you stop feeling the effects of a chemical
-in our modern world, we get dopamine hits all day long: social media, food, uber, door dash
-we are becoming intolerant to dopamine
-we need bigger experiences to feel dopamine (much like an addict needs more drugs)
11. How can you become more dopamine sensitive again?
24 hr FASTING - Resets dopamine receptors & pathways
RULES FOR FAST TRAINING WEEK (3 options)
BEGINNER LEVEL: 15hr fast, no refined sugar, flours, processed foods, break your fast with good fat
ADVANCED LEVEL: 3-5 day water fast
HAPPINESS FAST:
DAY 1 - AUTOPHAGY FASTING
- 17 hour fast
- break your fast with good fat
- protein under 20 grams
- net carbs under 50 grams
Purpose: clean neurons
DAY 2 - DOPAMINE DAY
- 24 hour fast
- ketobiotic meal
(50 g net carbs from vegetables,
50 g protein, 60% good fats)
Purpose: reset dopamine signaling pathways
DAY 3 & 4 - WATER FAST
- 48 water hour fast
- break your fast with ketobiotic meal
(50 g net carbs from vegetables,
50 g protein, 60% good fats)
Purpose: 3.5 increase in BDNF for better memory and concentration
DAY 5 - KETOBIOTIC REFEED DAY
- 17 hour fast
- ketobiotic meal
(50 g net carbs from vegetables,
50 g protein, 60% good fats)
Purpose: boosts serotonin
____________________
Reset Academy:
Dr. Mindy's Facebook Page:
Dr. Mindy's Facebook Group:
Resetter Podcast:
Dr. Mindy's Clinic
Sign Up for Dr. Mindy's Health News
Join the Resetter Group!
___________________
DR. MINDY'S NOTES:
1. What is chemically happening to us when we feel happy?
- Dopamine - happiness, pleasure, reward centers, sleep, memory, impulse control
- Dopamine is made in our brain (substantia nigra) & sent to our hippocampus (receptor sites)
2. What causes our brains to release dopamine?
-pleasurable activities
-food, sex, drugs
-social media, texts, etc.
3. Can we become addicted to dopamine? YES
4.Can we become intolerant to dopamine? YES
5. Do we need more dopamine releasing activities to feel the same effect? YES
6. Can we reset our dopamine pathways so we feel more happiness with less dopamine? YES
7. How do we do that?
LET’S TURN TO SCIENCE:
OBESITY & AGING:
-hypothesized that diminished dopaminergic neurotransmission in obesity may promote excessive food intake as a means to compensate for reduced sensitivity to reward (1).
-insulin & leptin resistance contribute to diminished dopamine signaling from midbrain
-obese patients were shown to have less D2 receptor sites to receive dopamine
FASTING RESEARCH:
-increased D2 receptors in rats
24HR FAST:
”Fasting caused a change in the properties of somatodendritic dopamine release, possibly by increasing dopamine release, and that this increased release can be sustained under conditions where dopamine neurons are highly active”
OTHER NEUROTRANSMITTERS;
Increase BDNF- improve dopamine signaling in hippocampus
Increase serotonin- precursor to oxytocin & melatonin, regulates moods, feelings of well being, helps you relax, sleeping, eating, and digestion.
Dopamine & serotonin have an inverse relationship.
-when dopamine goes up on a regular basis, your serotonin levels fall.
-when serotonin falls so does melatonin
8. Where are these two neurotransmitters made?
Dopamine- Substantia Nigra (brain)
Serotonin-90% in your gut (gut)
9. Where are the receptors for these two neurotransmitters?
Dopamine - 5 different types: Hippocampus, peripheral tissues including kidneys
Serotonin -15 different types of receptors: gut, nervous tissue (brainstem), skin, tastebuds
10. Can you become dopamine resistant?
Dopamine tolerance
-addicts know this, you need more dopamine to get the same high
-tolerance is the place where you stop feeling the effects of a chemical
-in our modern world, we get dopamine hits all day long: social media, food, uber, door dash
-we are becoming intolerant to dopamine
-we need bigger experiences to feel dopamine (much like an addict needs more drugs)
11. How can you become more dopamine sensitive again?
24 hr FASTING - Resets dopamine receptors & pathways
RULES FOR FAST TRAINING WEEK (3 options)
BEGINNER LEVEL: 15hr fast, no refined sugar, flours, processed foods, break your fast with good fat
ADVANCED LEVEL: 3-5 day water fast
HAPPINESS FAST:
DAY 1 - AUTOPHAGY FASTING
- 17 hour fast
- break your fast with good fat
- protein under 20 grams
- net carbs under 50 grams
Purpose: clean neurons
DAY 2 - DOPAMINE DAY
- 24 hour fast
- ketobiotic meal
(50 g net carbs from vegetables,
50 g protein, 60% good fats)
Purpose: reset dopamine signaling pathways
DAY 3 & 4 - WATER FAST
- 48 water hour fast
- break your fast with ketobiotic meal
(50 g net carbs from vegetables,
50 g protein, 60% good fats)
Purpose: 3.5 increase in BDNF for better memory and concentration
DAY 5 - KETOBIOTIC REFEED DAY
- 17 hour fast
- ketobiotic meal
(50 g net carbs from vegetables,
50 g protein, 60% good fats)
Purpose: boosts serotonin
____________________
Reset Academy:
Dr. Mindy's Facebook Page:
Dr. Mindy's Facebook Group:
Resetter Podcast:
Dr. Mindy's Clinic
Sign Up for Dr. Mindy's Health News
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