Understanding Diabetes Insipidus

This video contains a detailed and simplified explanation about diabetes insipidus. We discuss the differences between cranial and nephrogenic diabetes insipidus, the signs and symptoms, testing for diabetes insipidus including an explanation of urine and blood osmolality and the water deprivation test (also known as the desmopressin stimulation test) and how we manage diabetes insipidus.

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DISCLAIMER: This video is for education and entertainment only, and is not medical advice. This video should NOT be used for medical advice or to guide clinical practice. The Zero to Finals content should not be used in any way to guide medical decision making. Zero to Finals takes no responsibility for any actions taken or not taken based on the information provided. Local and national guidelines and senior clinicians are there to help you make decisions, not YouTube videos. If you need medical advice or information, seek it from an appropriately trained and licenced doctor or healthcare provider that can address your individual needs. Zero to Finals cannot guarantee the accuracy of information in this video. Please highlight any errors you notice in the comments below - thank you.

[HoopsMacabre]

This really was helpful, man. Thank you. I have Cranial DI. Five years ago in November of 2017, I started drinking lots of water after I was diagnosed with Brain Cancer. Now I know for a fact that, yes, the tumor did effect my Hypothalamus in my brain and that’s what I causing Cranial DI. I have had a Fluid Deprivation Test recently and I’ve been given a prescription for Desmopressin. Tomorrow I start taking it. Wish me good health and good luck!

[noonessam]

This chanel is God sent for struggling Med students. Thank you so much.

[jasmined]

This has been so good to watch! I was diagnosed with diabetes insipudus after a brain tumour at aged 9 . I feel like there us so little known about it. Often when I take desmoprssin along with various other medication people will ask "what's that for?" and if I just reply with diabetes they will often jump to the conclusion that I have type 1 or 2 diabetes. It's videos like this that start to bring about a bit more awareness to help get people diagnosed quicker and bring about understanding

[amandasarahi]

I came upon this series and didn't realize I had already subscribed. So far the best simple explanation and I retain the information! Thank you!!!!
-nursing student approved!

[harjii]

This was incredibly helpful! You broke the condition down into bite sized chunks and explained it in a way that was easy to understand and digest. Thank you so much!

[jparra]

I had cancer when i was 13. I had a tumor on my pituitary gland. So the gland doesnt work. I got diabetes insipidus among other things. I want to study it and understand it thank you for the video

[carrieberrykix]

We're testing our dog for DI right now testing with desmopressin. This really helped me understand what the vet was talking about!

[yourlocalfairyhere]

I have the cranial type of diabetes insipidus and I am on medication! What really triggered me to know more about this disease is that I actually have a pesenstion about diabetes mellitus in a few days and while preparing for it I realized, it really does not have anything to do with this type of diabetes and that I actually wanted to know more. Thank you for this

[dinosaurxxxx]

I had given up hope as to why I have to urinate very excessively, but now I have hope after finding out about this, going to mention it to my doctor and ask for testing! thank you!

[perkyiff]

came here for a quick recap back on the topic from my psychiatry revision after encountering DI as one of the side effect of lithium. thank you for the short and sweet explanation!

[jenrferruso]

THANK YOU!!! I WAS BORN WITH THIS 9/5/74 AND NOT DISCOVERED TIL 3/26/1996 AND NOW DISABLED FROM SEIZURE 10YRS TO THE WAY DISCOVED AND THE DRS GAVE ME MEDS AND 3MTHS IN HOSPITAL THANKFULLY GOT TO LIFE!!!! THAT GOD!!! PEACE BE WITH YOU!!!

[acidburstman]

Very helpful. The water deprivation test was confusing in my book. Here it was easy to understand.

[チミヤキ]

I have given up all hope of living abroad after frustrating attempts to treat an excessive thirsty and urination condition. Tanken a lot of meds to treat my prostate, said to be contracting incorrectly and I was even told to do a surgical procedure that wouldn't allow me to have children.

Then I changed doctor after doctor e one have told me to take desmopressin due to high level of urine/day (5L), it's been 3 week of 0, 1mg and my life changed so much, I'm a new person. Lately I have been facing these problems again, but I've been drinking lots of water due to anxiety, though I feel much better now in my life. Don't let this ruin your life, take good care of yourself.

[JHilariosaH]

This helped my family members understand my insatiable need for water. My pituitary gland was removed along with a brain tumor when I was 3 years old.

[jasondoyle]

Thank you for such a lucid explanation of the condition.

[jaredfernandez]

Great video and overview of the pathophysiology of diabetes insipidus! One critique, the arrow that is shown @ 2:44 of the video is vaguely misleading. It implies that ADH is released/produced by the anterior portion of the pituitary gland which is incorrect. The posterior pituitary gland releases ADH. Thank you for making such great work and I'm glad to see these concise and helpful videos. Thanks again!

[alexsekura]

This was extremely helpful. Thank you so much for taking the time to learn this content in detail and also for teaching the public.

[RyanS]

I was recently diagnosed with cranial DI due to radiotherapy 6 years ago. Thanks for helping to understand what exactly is happening to me.

[shreyasharma]

You are a very good teacher, who makes things easier. Thank you. Keep creating videos😊

[Tara-ddqn]

thank you so much I am a senior nursing student and found this very helpful