IDH Mutations in Cancer

Mutations in the genes encoding the cytoplasmic and mitochondrial forms of isocitrate dehydrogenase (IDH1 and IDH2, respectively; collectively referred to as IDH) are frequently detected in cancers of various origins, including cholangiocarcinoma (bile duct cancer). If you are newly diagnosed, please ask your doctor about biomarker testing to find out what genes, proteins, and other substances (called biomarkers or tumor markers) that can provide information about your cancer for personalized treatment options.

[manuelalejandrorodriguez]

Hi, my mother is a young woman of 69 years old, with all the desire and enthusiasm to live, that unfortunately have Cholangiocarcinoma. She made the biomarkers that report IDH 1 mutation. I want to know how can i get any therapy like ivosidenib or any other in Uruguay (south america)? She is without symptons rigth now and did not respond significantly to the conventional quimiotherapy.