Genes Linked to Lupus

Systemic Lupus Erythematosus is an autoimmune disease that predominantly affects women during their childbearing years. Seen more common in African-American, Native American and Hispanic patients. In Systemic Lupus Erythematosus, the immune system produces antibodies that cause inflammation and damage the body’s own organs and tissues. It is difficult to diagnose because its symptoms are similar to those of other immune system diseases. Some new observations have emerged to help direct future research to better diagnose and treat the disease. It also provides insights into why lupus disproportionately affects certain ethnicities at higher rates and more severely. The cumulative hit hypothesis, an immune system can normally absorb the effect of a modest amount of risky genes, but as the number of genes climbs the immune system becomes overwhelmed, resulting in disorders such as Systemic Lupus Erythematosus. There is a genetic predisposition to developing lupus and this study helps scientists to decipher the heterogeneous manifestations of the disease, which is hard to diagnose and treat. The ancestral distribution of these genes explains the ethnic disparities in Systemic Lupus Erythematosus.

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would like you to research if a wolves genetic structure is same as person with lupus