Biochemistry of ABO Antigens

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The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes.
Blood groups are inherited from both parents. The ABO blood type is controlled by a single gene (the ABO gene) with three types of alleles inferred from classical genetics: i, IA, and IB. The I designation stands for isoagglutinogen, another term for antigen. The gene encodes a glycosyltransferase—that is, an enzyme that modifies the carbohydrate content of the red blood cell antigens. The gene is located on the long arm of the ninth chromosome (9q34).
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Very easy to understand! You explained this better than my lecturer ever did! 🤝🔥

ruggedbypowell
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great simplification, just one thing : the FUT1 encoded by H gene is in the locus of the 19th pair of chromosome ( A and B alleles are in locus of 9th pair ) :)

anonymed
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Thank you sir, You have made a clear explaination of what others make so complicated. I like what you do and I think you should contine as you are clearly very talented.

joannabullen
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Very good teaching skills. Made easy to understand the general idea of ABO blood group systems. Thank you.

martinchan
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Beautiful Explanation. Simple and straight forward.

faizmohammadshee
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One mistake FUT 1 gene located on chromosome no. 19 not 9,
While explaining you said 19 but you written 9

ashokpatil
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Thanks a lot you made these things crystal clear to understand :) really appreciated.

ranikisku
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Thanks ☺...may Allah(s.w.t) bless u and keep continue blessing u always with peace and happiness and all the sucess in ur life of this duniya and hereafter😊

sahidasultana
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it is very easiest way of explanation of blood group thank you so much sir

guptaghanshyam
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Why you are so amazing! Always to the point. Thank you so much 🙏

komaldhyani
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Thank u so much
I was exactly looking for this

ellios
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Thanks a tonn.. U can't imagine how mch it helped me.. ❤

amayra
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Thank you sir for much better explanation

lipsunibedita
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Thanks a lot sir_ This topic had been irritating me. You made so simple and easy to understand_ ☺️

Ks-mokt
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Sir nice to knw abt the O-antigen😊....thnx fo the clarificatn

Micro-life
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Thnkq sir, for such a simple n understandable video .. it really hlpd a lot 😄

md
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Ur teaching method is so amazing 😍 thanks alot

Jaikrishna-bcgi
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Superb sir very awesome way of teaching love it 👍👍👍

doctordr
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Thank u for explanation of biochemistry of ABO antigen nd also for that H antigen.my blood grp is o -ve nd for these many yrs I was under impression that o blood type don't hv antigen.thanks again.

kavyamorya
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Thanks for the explanation i'm confused a little bit. The last video I watched started started the O-oligosaccharide sequence with galactose and ended with fucose but yours starts with glucose before galactose. How's that?

henrydillon