Antiarrhythmic Drugs

You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:

@1:05:28 The alpha subunit Inhibits AC while the beta-gamma subunit activates potassium channels.

Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Antiarrhythmic Drugs. We begin this lecture by reviewing Cardiac Physiology which will be essential in order to understand how these antiarrhythmics work. We will then go through the 5 types of Antiarrhythmic Drugs which include: Sodium Channel Blockers (Type I AAD), Beta Blockers (Type II AAD), Potassium Channel Blockers (Type III AAD), Calcium Channel Blockers (Type IV AAD), Adenosine + Digoxin (Type V AAD). After discussing these classes of drugs mechanism of action and indications, we will then transition into each of these types of drugs adverse reactions. We conclude this lecture by going over practice problems for Antiarrhythmic Drugs that we will be reviewing with you. We hope you enjoy this lecture and be sure to support us below!

Table of Contents:
0:00 Lab
0:07 Antiarrhythmic Drugs (AAD) Introduction
1:35 Cardiac Physiology
49:37 Beta Blockers (Type II AAD)
57:05 Calcium Channel Blockers (Type IV AAD)
1:01:03 Adenosine + Digoxin (Type V AAD)
1:14:06 Sodium Channel Blockers (Type I AAD)
1:31:54 Potassium Channel Blockers (Type III AAD)
1:42:33 Indications for Antiarrhythmic Drugs
2:02:04 Adverse Drug Reactions: Beta Blockers (Type II AAD)
2:07:42 Adverse Drug Reactions: Calcium Channel Blockers (Type II AAD)
2:09:42 Adverse Drug Reactions: Adenosine (Type V AAD)
2:12:47 Adverse Drug Reactions: Digoxin (Type V AAD)
2:20:10 Adverse Drug Reactions: Sodium Channel Blockers (Type I AAD)
2:27:26 Adverse Drug Reactions: Potassium Channel Blockers (Type III AAD)
2:33:36 Antiarrhythmic Drugs Practice Problems
2:40:25 Comment, Like, SUBSCRIBE!

Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.

Join this channel to get access to perks:

APPAREL |

PODCAST |

DONATE

SOCIAL MEDIA

@NinjaNerdSci

#ninjanerd #arrhythmia #antiarrhythmics

[fivebagsforlife]

I am a cardiologist and eventhough I know all these stuffs in my head I watched your videos to learn how to explain it so clearly to my students. However at this point I would just give them the link to your videos because I doubt I can explain it better than you with all these graphics😂 really well done!

[zeebalz]

You made this 5 days to my Pharmacology exams. You're a G

[fanzone]

Almost 3 hours of a video= hard work= tremendously helpful and valuable information being given, thank you!

[sofiaperan]

literally the best teacher in the world.

[tosanetsano]

I was literally just taught this topic this morning in my pharmacology class. Thank you for all you do, you guys have been a tremendous help in getting me this far in pharmacy school🙇🏾‍♀️🙇🏾‍♀️❤️

[joelfernandez]

This is hands down the best pharmacology/physiology channel on Youtube, thank you so much for making these Videos and keep them up!

[shrutikaldhone]

Your lectures help to clear the concepts about the particular subject.... our vision becomes crystal clear. No matter how many times I read antiarrhythmics, I used to get confused and frustrated. But hey, after watching this full video, I feel a lot confident about the topic now!! I really admire the efforts you guys put in to teach the subject. And I adore your capability to learn, understand and then teach any topic that you present. I am following you since a year now, and not a single lecture was there where I got bored or neglected the teacher 😉. You have the mesmerizing capacity to keep your audience glued to your lecture till the very end, and very few people in the world harbor this captivating ability... you stimulate me to study hard and harder. I can't thank you enough. Love you guys! Be blessed always. And keep teaching!!!

[VincentAubin-qzkp]

I've never seen a better description on the pharmacodynamics of the drugs and ways to remember them; perfect video for cramming for a test lol

[piyapatel]

The excitement and enthusiasm to know this, rubs off!! Hats off to him🙌

[tanzeelakakroo]

Hands down the best channel to ace any concept regarding any physiological concept . Can't believe u taught Arrythmias so well that no teacher or any other video on YouTube could have done

"Thanks for existing Zach "❤

[manyasfon]

I just got my “pass” on Step 1. I just want to thank you for your input - it can't be overestimated how much your videos helped to build the base.
Best wishes to you and your team! You are amazing!

[doskevin]

Quick tip to help you understand better:

Inside of cell is more negative than outside of cell AT REST. This means they are polar. Opposite charges (the old saying polar opposites). When a cell depolarizes (de=not) the inside of the cell is becoming more positive meaning they are becoming less polar. When the cell depolarizes (re= again), it is becoming negative again back to the resting state of the cell.

[Cole-mbdn]

This video is exactly what I needed for pharmacology rn! Crazy how Ninja Nerd just knows.

[devrajlamichhane]

This is the best description and way of teaching Cardiac physiology and Thank you Doctor for Hard-work.

[HEMZACHEMAA-iz]

Best teacher I found so far .
Thank you

[nghiapham]

This is GOLD! Your enthusiasm is palpable! Thank you very much!

[timothykruse]

I appreciate your videos. I'm a firefighter/Medic and I watch your videos periodically as a refresher. Your take on physiology and the way you teach fits my learning style perfectly.

[errrccc]

This just cleared a lot of my confusion about anti-arrhythmic drugs. Definitely worth to watch! Thank you so much!

[gabbygtz]

Congrats on 2m!!🥳🎉 u guys more than deserve it! from the bottom of my heart, thank you Zach and team for everything that you do! idk how I would be getting through PA school without ur help! Ninja nerd for life:)

[pkxplnq]

I seriously don't know what i would do without your classes.