Apoptosis

apoptosis is a form of programmed cell death where the cell undergoes morphological changes, to minimize its effect on surrounding cells to avoid inducing an immune response. The cell shrinks and condenses - the cytoskeleton will collapse, the nuclear envelope disassembles and the DNA fragments up. This results in the cell forming self-enclosed bodies called 'blebs', to avoid release of cellular components into the extracellular medium. Additionally, the cell membrane phospholipid content is altered, which makes the dying cell more susceptible to phagocytic attack and removal.[17]

Apoptopic caspases are subcategorised as:

Initiator Caspases (Caspase 2, Caspase 8, Caspase 9, Caspase 10)
Executioner Caspases (Caspase 3, Caspase 6 and Caspase 7)

Once initiator caspases are activated, they produce a chain reaction, activating several other executioner caspases. Executioner caspases degrade over 600 cellular components[18] in order to induce the morphological changes for apoptosis.

[rickfearn]

Thanks, Thomas. What is the text book you are referring to, please?