Vasculitis Pathophysiology Overview

"Vasculitis is inflammation of the blood vessels resulting in damaged vessels leading to potential complication such as tissue ischaemia from lumen narrowing or from thromboembolic events from platelet consumption during vessel repair. Vasculitis classically refers to arteries rather than veins. Vasculitis can be primary or secondary. Primary being its own disease and secondary being secondary to a drug, disease or cancer. Primary vasculitides are classified into the size of the blood vessels affected; large vessel vasculitis such as those disease affecting the aorta and its main branches, medium vessel vasculitis such as those affecting branches of the kidneys and small vessel vasculitis which affect the arterioles and capillaries. The medium and particularly the small vessel vasculitis are the type which present with cutaneous, skin findings such as purpura and petechiae because the smaller blood vessels are more superficial.

The pathophysiology of vasculitis is unclear, but is thought to be primarily immune mediated. Because there are different types of vasculitis the pathological findings and therefore the pathophysiology would be slightly different."

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[armandohasudungan]

🎥 DON'T JUST WATCH, LEARN ACTIVELY! TRY THE QUIZ! 🤓

[joshuathompson]

I’ve had vasculitis since I was 13 now 28 best breakdown I’ve ever seen. I was treated with prednisone and now keep it in check with methotrexate.

[sciencelife]

U r the reason I started taking notes in my med school. Hats off to you!

[fatimasuleman]

Thank you so so much.. you are really helping a lot and lot of med students and that also for free. Thank you so much. Keep up the great work .

[jschoeneck]

One of the best explanations! Thank you!

[glizbpr]

Thank you. Helps me understand the dangers of the Spike Protein.

[Agni]

Thank you so much for a wonderful explanation.

[francocuevas]

Excelente presentacion! Muy buena integracion de los sindromes y su presentacion. Muchas gracias.

[arturmunteanu]

Thanks very nice but too late...had this to study last week and it was sad without your video :(

[DhanushkarRavindran]

Great video 👌
7:31 should be corrected as vessel wall injury

[johnscallan]

At 3:51 my eyes roll back in my head and I slump into a coma. A symptom of?

[NoCommentChick]

Is it a meme yet to complain that Armando’s covering something you just got tested on?

[chinmaypatwardhan]

Is renin a hormone or enzyme plz explain

[kanchanthakur]

I just saw draw.not see word.plz increased size of word.so we can understand very easily.


Nicee viedo

[affysyifarani]

thank you so much, you're the best

[howtomedicate]

An other fantastic video! WOnder how you keep making them, haha! Keep it up!

[ruanfamilytv]

At 5:58, when antibody is binding to neutrophils, should the Fc portion be binding rather than the Fab region?

ps. love the videos. they are super helpful

[annasutton]

I am not a med student, I have a friend who has Leuksklastic vasculitis. Sorry if spelling is not correct. I am led to believe this is quite rare.
She does not seem to get much relief from the disease. She more often than not has purpura on her feet and legs. These are very painful and have to be dressed. Some turn into open stores if not treated.
It's a horrible disease, painful and debilitating. She also has Parkinsons disease and colitis.

[elvinisa]

Nice.
Please take off Diabetic Nephropaty👍🏻

[saeelnaik]

No one ever will or can come close to Dr. Najeeb in explaining medical sciences.. He's the god of medicine