Lipoprotein(a): Who's Most at Risk

Stanford Univerisity's Dr. Khandelwal and Family Heart Chief Medical Officer Dr. Mary McGowan outline who should have their Lp(a) tested and what to do with those results. #KnowLpa

[numberthree]

Lp(a) is a risk factor, not an absolute sentence to cardiovascular disease. My doctor says "80% of CVD is environmental." So, as the video says, don't smoke, avoid obesity and diabetes, don't eat junk food, exercise, etc. Plenty of people with high Lp(a) values (which supposedly is inherited in a co-dominant fashion) never develop CVD nor have their parents and other close relatives.

[Orlando-Paul]

As someone with High Lp(a), this was the best source of info on the topic I have seen. Thank you for a great presentation

[jillmorton]

Thank you for the webinar. I shared it in my lpa/ heart attack Facebook groups

[JMK-vopv]

Dr. Khandelwal, are you familiar with the Lp(a) work done by interventional cardiologist, Dr. Nadir Ali, from Webster, Texas? Dr. Nadir Ali not only opines that Lp(a) has NOTHING/ZERO to do with CAUSING atherosclerotic diesase (CAD, CVD), but he describes Lp(a) as a very important molecule in the repair process of damaged tissue. Dr. Ali describes some elderly patients, with lifelong high Lp(a) levels, who he has performed coronary angiograms on, and these patients have absolutely NO plaque whatsoever.

[Bbarfo]

I have high LP(a) for many years. I'm 64 and my CAC is 32. I keep low carb/sugar, intermittent fasting paleo/keto eating lifestyle. Low inflammation and healthy blood pressure is the key.

[sammschmitz]

Excellent presentation. Very informative.

[jeffm.]

Per Linus Pauling and Mathias Rath, LP(a) is a marker for scurvy (vitamin c deficiency) in the arteries. I reduced my LP(a) almost in half with high dose ascorbic Acid.

[whobdis]

I was to be in a trial to reduce LPa (mine was in the 245 range). The followup prior to be in the trial my LPa was at 150 which was to low to be in trial. The only thing that changed was I was put on Repatha maybe 3 weeks before the followup. 150 is still high but it's been in that 240..250 range for about 10 years.

[edwrobel]

After six weeks of 2000 mg per day Niacin treatment my Lp a dropped from 147 nmol/l to 45. I begun another six week 1000 mg Niacin treatment.

[captainnoyaux]

how much aspirin was taken, how much per week ?

[Freedom_Now_and_Forever]

Would a natto kinase supplement be recommended?

[seascape]

If PCSK9 inhibitors are not FDA approved for LP(a) reduction, does that mean a physician cannot prescribe it off label? And will the pharmacy plan be less likely to pay for this more expensive drug being it is not FDA approved for that usage?

[inaratolocko]

Yes, statins increase lip (a) significantly for people with genetic abnormalities, for example - family hipercholesterinemy

[henryverwey]

Thanks for your presentation. As far as LP(a) levels it seem that the measured levels can differ when considering either mg/dl or nmol/L, they appear not to be interchangeable although 2.5 is being used as a converting number. Any comment on that? Thanks again

[inaratolocko]

After rosuvastatin I have lip (a) 517. I will try PCSK9 inhib.

[edwrobel]

Check with the doctor? You have good sense of humour

[groovetube]

There are some old studies showing that androgens (testosterone, anabolic steroid) lower lp(a) by 60-80%. People who take testosterone replacement or anabolic steroids could be benefiting from it. Has anyone studied this?

[tipskulhiso]

I have normal LPa 48 but high ApoB 134. Which one would help my heart or kill me?

[CaroleLauzon]

Can it cause pulmonary embolism in lungs?

[michelpaulussen]

If you have high LPa and you are metabolic healthy (low carb) and you do not smoke then you enjoy the highest protection from living to a very old age BUT IF YOU NOT HEALTHY AND YOU ARE INSULINE RESISTENT AND YOU SMOKE THEN YOU HAVE THE HIGHEST RISK TO DIE EARLY