Tissues, Part 3 - Connective Tissues: Crash Course Anatomy & Physiology #4

On today's episode of Crash Course Anatomy & Physiology, Hank continues our exploration of tissues, with an introduction to your connective tissues.

Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App!

Chapters:
Introduction 00:00
What is Connective Tissue? 2:14
Four Classes of Connective Tissue 2:34
What Makes Connective Tissues Different From Other Tissue Types? 3:25
The Extracellular Matrix 4:07
Types of Fibers 5:34
Connective Tissue Cells 6:34
How Marfan Syndrome Affects Connective Tissue 8:31
Review 9:37
Credits 10:08

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[anitacheung]

Function of connective tissue (most abundant tissue in the body)
1. Binding and supporting
2. Protecting
3. Insulating
4. Storing reserve fluid and energy
5. Transporting substances within the body
6. Movement

Types of Connective tissue
• Proper connective
◦ Fat - provide insulation and fuel storage
• Cartilage connective
◦ Most - avascular (no blood vessels)
• Bone connective
• Blood connective
◦ Transportation

Characteristic of Connective tissue
• They are all develop in the same origin - Mesenchyme - loose and fluid embryonic tissue
• Different degree of vascularity and blood flow
• All connective tissues are mostly composed of nonliving material - extracellular matrix

Extracellular matrix components
1. Ground substance -
- A watery, rubbery unstructured material that fills in the spaces between cells and protect cell from their surrounding
- Flexible, made of starch and protein molecules mixed with water
- Proteoglycans (protein) from each sprouts lots and lots of long, starchy strands called Glycosminoglygans (GAGs) radiating out from those protein.
- It clumps together to trap water
2. Fibers
- Provides support and structure to the shapeless ground substances

Types of fibres
• Collagen fibers (protein)
◦ Strongest and most abundant type of fibre
• Elastic fibers
◦ Long thin, a branding framework within the matrix
◦ made out of protein elastic
‣ Allow to stretch and coil
◦ Find in skin, lungs and vessel wall
• Reticular fibers
◦ Short, finer collagen fibres
◦ With glycoprotein
◦ Form sponge like-networks that cradle and support

Immature cell are called blast
• Means forming
• Stem cells still dividing and replicate themselves
• Function: to secrete the ground substance and fibres that form its unique matrix

Types of immature cells (blast --> cytes)
• Chondroblasts - the blast cell of cartilage
• Osteoblast - the blast cells of bone tissue
• After blast they develop into cytes, but cytes can go back to blast, if they need to repair or generate a new matrix


PS: Thank you for all the thank you sss ~ btw I find it hard to watch the whole video RIGHT before an exam, that's why I "copy and paste" it. I hope it helps :)

[derekmccloud]

Fun strategy I've been using to maximize retention from these videos: Try watching it with the sound off and explaining the concepts out loud yourself. You'll quickly figure out what you need to revisit!

[lailatrindade]

You know this educational method is revolutionary when you see yourself watching these videos and learning just for fun. <3

[CebollaCreek]

I'm learning more from this guy than from my actual A&P prof

[OsirisMalkovich]

The most amazing thing about Flo Hyman is that the fact that her name was "Flo Hyman" wasn't the weirdest thing about her.

[ThatFangirlZebra]

As someone who suffers from Ehlers danlos syndrome (a mutation in the collagen in the body) with Marfanic tendencies, as well as an aspiring medical physicist,  I was waiting for you to do a connective tissue crash course. This video will make it a lot easier to explain to people who do not know the extensive functions of connective tissue. Thankyou very much Hank, very helpful. 

[BooksToAshes]

But does Flo Hyman wear size 13 in Nike's....MENS?
Didn't think so.

[deeyoyo]

So I suffer from EDS - which is a mutation of collagen in connective tissue - AND I SWEAR I HAVE NEVER KNOWN MORE ABOUT WHY MY BODY SUCKS AT BEING A BODY THAN I DO NOW, THANK YOU

[lorighirsm]

I'm a med student in italy, and in febraury i'm taking histology exam... your videos really helps me through my study, so, once again, thanks Hank for your awesome job! :)

[sedbehappy]

Thank you for talking about Marfans! I have EDS but it's so exciting to see either getting awareness, especially with so much other helpful info :)

[bellab]

I am so happy Marfan syndrome is getting some recognition. My mom was not diagnosed with it until she was 18 and my grandpa was not diagnosed till 45. It's crazy.

[SilverZephyrFalcon]

I've never heard someone talking about Marfan Syndrome on YouTube, or even outside of my fraternity. So excited that you've helped others learn about it!

[NicoleTrawick]

I am in A&P I, taking my first test tomorrow. These videos are great study guides to go along with my textbook, notes, homework and quizzes. You guys are great!

[crashcourse]

Pssst... we made flashcards to help you review the content in this episode! Find them on the free Crash Course App!

[br]

I'm a first year nursing student and this is a brilliant way to get started on some of the concepts i'll be learning about. Very tasteful balance between light hearted and informative. great stuff.

[Bram]

0:05
"9 years later she made it to the 1984 Olympics"
Me: yay I feel confident in myself!

"she collapsed and died during the game"
Me: Well... Shit

[hm-mtwj]

All that I can think of while watching this is...

I want that Angler Fish Plushie.

[stevensosa]

Idk why I find anatomy so fascinating love this series

[oliverm]

you should make online college course that award credits

[alexevans]

used these to study for science olympiad YEARS ago, got first place city wide and second state wide.
forever will love crash course!!!!