Transcription Process | Gene Expression | From DNA To mRNA | Class 12 Biology

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About This Video ........................

In This Video Lecture You Will Learn Basic Concept Of Transcription

This is the process in which an RNA copy of the DNA sequence encoding the gene is
polymerase II, which synthesizes mRNA and RNA polymerase III which synthesizes
The opposite strand is called coding strand or the sense strand. The RNA polymerase
tRNA.
also called -35 sequence and TAT A AT sequence also called -10 sequence, which have
The binding of RNA polymerase to the promoter is the irst step in gene transcription.
ainity for the RNA polymerase. In eukaryotes these sites are at -75 and -25 sites,
of DNA are transcribed. This strand is called template strand or the antisense strand.
from the bubble (Fig 20.25). The stop sequences at the end of the gene terminate the
followed by four or more U ribonucleotides. The hairpin causes RNA polymerase to
and completes the transcription of the gene. The DNA strands open up at the place
synthesis of mRNA. The simplest stop signal is a series of GC base pairs followed by a
polymerase in prokaryote which is responsible for the synthesis of all the three types
and the remaining part of the enzyme (core enzymes) moves over template; strand
produced with the help of an enzyme, RNA polymerase. Only one of the two strands
of RNAs viz. rRNA, mRNA and tRNA. On the other hand there are three types of RNA
of transcription process. Once the transcription has started the sigma factor is released
where enzyme is attached to the templete strand forming transcription bubble. The
Transcription starts at the RNA polymerase binding site called promoter on the DNA
template strand. In prokaryotes within promoter there are two binding sites TTGACA
polymerases in eukaryotes namely RNA polymerase I, which synthsize rRNA, RNA
transcription bubble moves down the DNA, leaving the growing strand protruding
respectively
series of AT base pairs. The RNA formed in this region forms a GC hairpin (Fig 20.27)
enzymes synthesize RNA from 5’ —» 3’ direction. There is only one type of RN A
One of the subunits of RNA polymerase sigma factor, is responsible for correct initiation
stop synthesis.
In bacteria the newly synthesized mRNA is directly released into the cytoplasm, when it
form of 7 methyl GTP, which is linked 5’ to 5’ with the nucleotide, whereas tail is in
that the molecule may remain stable during long journey to ribosome. The cap is in the
is converted into polypeptide chain. In eukaryotes however, it has to travel long distance
from inside the nucleus to ribosomes outside in the cytoplasm. The eukaryotic mRNA
the form of poly A tail linked to 3’ end of the RNA. These caps and tails save the mRNA
is therefore modified in several ways to aid this journey. A cap and a tail is added so
from variety of nucleases and phosphatases.

About This Channel.....................

I make these videos cause I love to draw and connect the complexity of science and medicine into art. I'm not saying. I'm 100% correct in all my videos, but I do try to obtain the information from credible sources.
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2 years back i take the same lexture in my fsc part 2, but now in mbbs 1st year i take this lec again bcz of easy explanation ❤❤❤ sir you are gem 😊

MedicalstudentNabaMateen
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Literally no body explained this well on Youtube in short time the way you did

snehashahid
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Sir Ap Itna a6a smjaty hn
Mgr Sary topics nhi hoty upload is liay bht Mushkl hoti h.
Plz class 12 ke Sary topics upload krdy
جزاک اللہ خیرا

fazishah-eudd
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Fav dialogue "Jo k bht asan or simple sa topic ha"

HadiaShaukat-hzdf
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love from India you are the best influncer

achchenotes
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Jazaak ALLAH sir apky lactures BHT achy sy samjaty h

atiqali
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Trust me you are the bestest teacher in the world 🌎✨🩵

SabaKhan-wktd
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in a little bit of time, you explained the topic in a fervent manner..
I am very grateful to you...

hassantanveer
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Bhut zabardast mai na bhut ziyada video daky but app ka method bhut Pasand ayaha

AbdullahAli-np
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Fav thing jo k pyary bcho boht asan sa or simple sa topic ha😂😂

irfanch-szfp
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Sir Jo mushkil words hai English ke unki meaning bhi bataya kare wese bht acha samjh me ata hai apka Thanks sir ❤

smileforever
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Thank you so much sir itne time mein itna jyada content dene ke liye

aalok-YT
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-35 sequence 5prime TTGACA 3prime
-10 region start site 5prime TATAAT 3prime
In prokaryotes...

huzaimkhan
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Assalamualaikum sir
App k lecture buht kamal k hn mujy aik topic smjna h Coenozoic era kindly ap os k bhi lecture dy dn mujy app ki bhut achi smg ati h plz...

syedmuneebabbas
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Mashallah very nice explination allah aapko jazai khair de ameen ❤️😊🤲

akeelguhagarkar
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Thanks sir
You have explained all the topic in easy way, just like eating a 🍞

Collegekaladka-jj
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Jazaak Allah sir🥰
Other lectures of this topic is so lengthy....but its length is right and concepts are also cleared 👍

buttzahid
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Sir mera b pharma 2 sem hai . transcription topic hai biochemistry me kya ye jo bataye hai ye likh denge to kya full marks milega .

student-hxtn
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Sir topic asasn or simple sa hota nhi Hy AP bna dy ty hn, well explained ❤️💯

EMAN_FATIMA_
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Very very very very great understable sir thank you so much

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