Applications of NGS in Oncology: A perspective on targeted sequencing in a clinical setting

Dr. Margarete Odenthal, from Laboratory of Translational Pathology of University of Cologne, Germany, shared her recent studies on oncology using a targeted sequencing approach. In this presentation, she discusses the adoption of targeted sequencing in a clinical setting, including the use of gene panels for studying sequence variants, copy-number variation, and mutations in the mitochondrial genome. Considerations in sample and library preparation, sequencing, data analysis and interpretation are also discussed, with a particular focus on the implications of these data for patients.