Patrick Dempsey REACTS to Ellen Pompeo's Grey's Anatomy Exit

Patrick Dempsey reacts to Ellen Pompeo seemingly leaving 'Grey's Anatomy.' On 'Jimmy Kimmel Live!' the actor and host joke about Ellen’s Instagram post, where she seemingly bids farewell to her character, Meredith Grey after 19 seasons. Ellen writes, 'I am eternally grateful and humbled by the love and support you have all shown me, Meredith GREY and the show for 19 seasons!'

[gabbygriggs]

400 episodes is a crazy milestone, and to still be going (for however long) is wild. Meredith Grey became Ellen’s entire career, and I’m sure that isn’t what she expected when she first put on the scrubs. Thank you for so many seasons of memories watching with my mom and my friends, for always giving us something to talk about at school or work on Friday. I was 9 in 2005, I’m almost 27 now. Grey’s has been around for so many era’s of my life it feels weird for it to move on without Mer. But I know I’ll still be watching come February, because of course, the carousel never stops turning.

[doquewias]

I'm heartbroken and sad to see her go but she deserves to take a step away from it all

[sarawinardi]

This is like ‘The Office’ without Michael and ‘The Vampire Diaries’ without Elena. We all know how long that lasted

[thatfatginger]

I feel like 20 seasons is a good number to end on

[biddyreid]

She is every TV shows dream actor. The dedication and encouraging them to go beyond her, being so involved to the point it's behind the camera too?!

[amiragraham]

The show lost a lot by killing off so many people : Derek, Lexi, Mark. There’s no room for so many great characters to even come back

[littlemissbookfeen]

This show will forever hold a place in my heart, Meredith Grey especially. On my way to becoming an obgyn because of my love for it through just watching. Ellen paved the way for sure

[thereallg]

*the show isn't going to last without her.*

[Jumbaride]

Not gonna lie... I'm a little heartbroken. But I think this will be a positive step for Ellen, and it might also breathe some new life back into the series with such a major change-up. Time will tell, but I will continue to support my Grey's family.

[amandam]

The show isn't going to be the same without her. But she has given us 19 years of her life. 19 great seasons. I can't wait to see what she does next. I feel like the show is coming to an end though, we have lost so many great characters over the seasons. Definitely a bittersweet moment. 😒

[cinephile]

How will it still be Grey’s without Grey? The show’s had so many strong characters leave that it’s pretty much hanging on by a bandaid…

[userA-a-p]

Meredith Gray IS the Gray's Anatomy, she can't leave. The show won't be the same without her and of course it won't last...

[BrotherRoy]

I'm one of those who spent 20 years in active addiction so I missed a lot during that time. Thankfully, due to technology, I'm able to download whole seasons/shows and watch at my convenience and Grey's Anatomy was one of them. Having finished ER I was looking for a similar show and this show, Grey's Anatomy totally enveloped me with such good acting, writing and personalities. I have binged on it so much and it's been a good "high"! Even now, I won't watch the current season until it has finished and I can watch one episode right after another without waiting for it to be aired. When Christine Yang left, a significant part went with her, being she was my favorite character, and to say the show can continue after Ellen having left I think we're only fooling ourselves. She has been blessed to have had such a positive and secured future during her working career and we have been blessed being a part of that experience. I wish her and all the supporting actors and actresses continued good fortune.

[jacintha]

Personally, I don't think I'll continue to watch this current season with her not being around, I bet it'll feel weird watching the show without her like the way I felt watching the show without Dempsey, but one thing is for sure though, I'll still rewatch previous seasons, watching old episodes brings nostalgia, gives out amazing energy. (specially seasons 1-5)

[thechosenpit]

This show has genuinely inspired me to consider taking my psychology degree into the medical field, and not only that, but it’s inspired me to push forward despite any and all hardships, to be a shark when I need to be, to be a shoulder to cry on for my people—that’s another thing it’s taught me; family isn’t always blood. You can choose your family and I have. I love this show, I love her, and I’m sure I’ll still be watching it years from now lol!

[vicstorms]

Oof this is truly the beginning of the end. But what a ride. I watched when the first episode came out back in 2005 and I can't believe the show is still running in 2022. Its truly a soap opera, ran for so many years and most of the original cast is not there anymore.

[VasilBorisov-lxte]

I cannot stop crying... End of an era... I cannot watch without her, she is everything in this show... 😭😭😭

[Alicia]

I didn't quit after George, I didn't quit after Lexi and Mark, not after Derek, *almost* after Alex. But Meredith is where I draw my line in the sand. She is the show. And Ellen herself has said over the last few years she was wanting it to end too. I understand the writers want to keep the show going but Shonda has said when Ellen is done, so is the show.

[sowhat]

I wish I could meet Ellen. She will never know the impact that her character has had on women like me. ❤️

[TLForsberg]

Ellen pompeo is a true artist and understands when a shift needs to come for the greater good! I love this! She is a powerful woman. I deeply look up to her! She rocks!