BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

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BRCA1 and BRCA2 Mutations & Cancer (Types of Cancer, and Who’s Most At Risk)

BRCA1 and BRCA2 are genes involved in DNA repair and other important functions. However, mutations in BRCA1 and BRCA2 increase the risk of different types of cancer, including breast and ovarian cancer. In this lesson, we discuss the roles of normal functioning BRCA, different patient populations most at risk, different mutations, and different types of associated cancer.

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JJ

**MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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[constancetorbert]

Great informative video for anyone, medical or not, to understand BRCA1 and BRCA2 !!

[thewrngchild]

I'm from an Ashkenazi Jewish background and me, my mum and my sister have just tested positive for BRCA2 mutation. It's good to know, you basically have the chance of beating cancer before you even get it if you get the test. I would highly recommend getting the test if you have Ashkenazi descent, or any other of the high risk groups.

Having a BRCA 1 or 2 mutation also does NOT mean you will DEFINITELY get cancer either, it just means you have an increased risk. Having the mutation entitles you to more frequent screening as a first line. I haven't decided yet if I will eventually opt for a mastectomy. My situation is complicated by other factors, so I am not sure what decisions I will make yet.

The one that worries me the most is pancreatic cancer. There has been more than one instance of pancreatic cancer in my family. Diabetes also runs in my family as well.

Be aware of your body and what is normal for you, if you notice any changes in your breasts, periods, like bleeding between your cycles, or develop any symptoms in your abdomen, go and get it checked out. It's likely not to be cancer, but you can mitigate the risk by getting it checked out early. Most cancers caught very early can be successfully treated. However the pancreatic one is much harder to detect, and is usually detected when it is advanced. There is also no screening program available for this one.

If you smoke, stop. Smoking is one of the biggest risk factors for pancreatic cancer. My dad died from what we think was pancreatic cancer, and he smoked all of his life. He wasn't of Jewish descent, and we will never know if he too carried a faulty gene because when he died in 1991, this kind of genetic testing wasn't done on a routine basis. Thankfully none of us three smoke, and I am teetotal.

[pattimcaninch]

This information is very helpful. I was diagnosed with invasive ductal breast cancer a couple weeks ago. I had genetic tests done and they found I had a defective BRCA2 gene.

[Kai-AI-hc]

Hello
Please expand your oncology playlist
Thank you ❤

[kusemono]

Great video, I would love to see something focusing specifically on oncogene's.

[kathyerb]

Thank u for this. BrCA, my daughter has this. However I don't. She has 1 daughter with BRCA1 age 4 with this, 3 other kids aren't tested.

[ThinkAboutit]

few week ago I felt some pains and I went to the hospital my doc told me I had Herpes about 1 yr and I need to start the treatment early from dr oigiangbe 💯

[Rosa-hfij]

My friend got breast cancer and no one in her family had breast cancer she passed after 3 years

[jayaprakashrao]

Are these genes associated with metabolic syndrome...??

[robertobobby]

Obesity factor it's the reality
Cancer prevention right nutrion

[ThinkAboutit]

few week ago I felt some pains and I went to the hospital my doc told me I had Herpes about 1 yr and I need to start the treatment early from dr oigiangbe 💯