Basal Ganglia | Structure Function | Neuroanatomy | Dr Najeeb

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Basal Ganglia | Structure Function | Neuroanatomy | Dr Najeeb

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00:00:00
Basic anatomy, location of Thalami, Caudate and Lentiform nuclei and Internal Capsule, and other structures in the base of the brain

00:12:47
Insula, Putamen, Globus Pallidus, Subthalamus, Midbrain, Superior and inferior colliculi, Substantia Nigra, Amygdala

00:19:29
Basal Ganglia classification: Traditional and Clinical

00:23:55
Corpus Striatum, Neo Striatum, Paleo striatum classification, Lentiform nucleus

00:29:10
Corticospinal fibers, Corticonuclear/Corticobulbar fibers

00:37:11
Initiation of idea/message: Prefrontal cortex, Primary, pre-and supplementary motor areas

00:40:20
Corticostriatal pathway-(up to)-Thalamocortical pathway

00:44:35
Neurotransmitters; Glutaminergic, GABAergic fibers/neurons, Increased firing of Inhibitory/GABAergic fibers at times of motor rest and vice versa; [Direct pathway]

00:57:15
Indirect pathway [involves subthalamus]; Glutaminergic pathway,

01:05:47
Substantia Nigra, Role of Dopaminergic fibers [Nigrostriatal pathway], Initiation of movement, its role in balance and fine-tuning through controlling of the previous two pathways. Counter-balancing act of Cholinergic neurons.

01:31:25
Summary/Revision of all pathways and structures.

01:35:35
Basal Ganglia Lesions [Direct Pathway lesions] causing Hypokinesia: Parkinsonism & Parkinson's Disease: Masked Facial Expressions, Serpentine Look, Lead pipe Rigidity and Pin Rolling Resting Tremors.

01:51:06
Drugs induced Parkinsonism: MPTP-associated Parkinson's, role of Dopamine Receptor blockers (Antipsychotic drugs)

01:53:06
Basal Ganglia Lesions [Indirect Pathway lesions] causing Hyperkinesia/Dyskinesia: Huntington's Disease.

01:59:30
Hyperkinesia; further explained: Chorea; Huntington's chorea, St. Viton’s' dance/Sydenham chorea, Wilson's Disease/Hepatolenticular Disease

02:12:34
Hyperkinesia; continued: Athetosis, Choreoathetosis, Dystonia, Ballismus/Hemiballismus, Tardive Dyskinesias (Dopamine Receptor Blockers use)

02:23:21
Rapid review of a full lecture.

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[AkhyansuPattnaik]

this is 1 of the most difficult topics to understand in neuroanatomy & this man just explained it so lucidly. i wish we had teachers of this caliber in india. its almost jaw dropping to watch someone having so much clarity in topics as complicated like this.

[dbkhatrychhetry]

I am a family physician, working in my private hospital. I am following dr Najeeb' lectures. I don't know where you are now, but every medical fraternity will remember you forever after listening your method of teaching. You always make nice tracks through a complicated forest. Thank you for these lectures. I have great respect to you and want to see you really.

[mohamedumar]

Nowadays seeing your lectures daily helps me a lot to understand easily neuro concept, I'm blessed to have a good professor in my you tube medical college
Thanks a lot Dr . Najeeb sir

[amjadnadeem]

I had seen tons of videos and books for Hyperkinesias but failed to get them during graduation years. Your 10minutes clarified everything. I will pray for you on your contribuition. Thanks alots.

[aeshaaesha]

Your students are so lucky they have an amazing teacher like you.... i wish u were my teacher in my medical school ... i would have topped .... you are a legend sir !!!

[AshokKumar-mjrg]

Because of you I am fall in love with neuroanatomy. Your videos are amazing.Thank you so much sir.

[nhilistickomrad]

First month i saw Dr najeeb, I was amazed and impressed.
Next month I was like this guy ain't special.
3 years later, this guy deserves some kind of order of something kinda lifetime achievement award for his work.

[bellaswan]

Am studying pharmacy but no Dr. In our college can explain the subjects we have like the way you do .you made me love physiology.
Thanks alot and god bless you

[docPriyangshuSharma]

Marrow/Dams/Bhatia/prepladder crying in the corner after watching his concepts

[plabifywithayesha]

Dr najeeb you're a blessing to all of us. There's not a single person who has not studied medicine from you. ALLAH apko khoobsoorat Zindagi de aur akhirat bhe bey intiha khoobsoorat bana de. Ameen

[Parrotlovefly]

hello from Ukraine . I liked your lectures sooo much. I could never think that such things can really be easy . You are really a great teacher )))

[kashaftahirr]

I wish literally I could take your live class lectures YOU ARE DEFINITELY SO GOOD AT DEVELOPING CONCEPTS!! THANKYOU VERY

[samwelngare]

We can't find the perfect professors in colleges and universities who can explain these things clearly only Dr. Najeeb can do so .

May the Lord Christ bless you abundantly and gives you more years to live in this world .

[saubhagyaswain]

SIR, these are mindblowing lectures.... pls keep adding such lectures.
The best teacher I had ever seen🙏🏻

[saiajay]

now i am actually a final year medical student, all these days i just mugged up direct & indirect pathways, without even knowing why they were called direct/indirect in the first place !!!!😂(there's a ton of difference between studying to pass exams & studying to enhance understanding)..thank u so much dr.najeeb, u teach so beautifully in this era of exam oriented learning !!!!

[sushmatomar]

Hello Sir!
You are really a fantabulous teacher. Nowadays, I am daily watching your videos to polish my Neuroanatomy.

[maheenjaved]

Before taking the lectures I think that it is going to be too lengthy and I don't have that much time.
But after watching them, I just know that all the time was worth it and these topics are crystal clear and wouldn't need anymore effort!
Everytime I watch your lecture, I pray that may Allah bless you more and more♥So thankful for a teacher like you💫

[MuhammadUsman-nosf]

Sir really you are a legend teacher and blessing of Allah for all medical student.

[karishmakhan]

Thank u so much sir❤❤❤May Allah give u more success, long and healthy life ...!!! Ameen suma ameen

[whcluow]

I HAVE NO WORDS TO EXPRESS MY SURPRISE DAY AFTER DAY & LECTURE AFTER LECTURE. JUST THANK YOU