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Neural regulation of blood pressure - baroreceptor and chemoreceptor reflexes
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• The nervous system regulates blood pressure with two reflex arcs: baroreceptor and chemoreceptor.
■ Baroreceptors (pressure) and chemoreceptors (chemical) are located in the carotid sinus and aortic arch.
• Carotid sinus reflex helps maintain normal blood pressure in brain.
• Baroreceptors are stimulated by the changes in the stretch of the carotid sinus wall; nerve impulses propagate from the baroreceptors over glossopharyngeal nerves to the CV center in the medulla oblongata.
• Aortic reflex maintains general systolic blood pressure.
• Baroreceptors in the wall of the ascending aorta and the aortic arch send impulses over vagus nerves.
• If MABP drops, there is less stretch and fewer signals sent to the brain stem.
• CV center sends out more sympathetic and fewer parasympathetic impulses.
• Decrease in parasympathetic impulses increases heart rate and CO.
• Increase in sympathetic impulses increases heart rate, myocardial contractility, venous tone, and CO.
• Vasoconstriction of small arteries and arterioles increases SVR.
• Increases in both CO and SVR cause MABP to rise back toward normal.
• Reflexes also work in the opposite direction.
• If MABP increases stretch then sensory nerve impulses increase. • Sympathetic impulses decrease; parasympathetic impulses increase.
• Decreases in both CO and SVR cause MABP to lower back toward normal.
• Receptors in carotid and aortic bodies detect chemical changes (O2, CO2, and H+') in blood level.
• Such conditions as hypoxia (lowered O2), acidosis (increased H+), or hypercapnia (excess CO2) stimulate receptors to send impulses to CV center.
• CV center increases sympathetic stimulation to arterioles and veins.
• Increases in SVR, CO and venous tone cause MABP to rise back toward normal.
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