Virology Lectures 2019 #7: Transcription and RNA Processing

When double-stranded DNA viruses infect a cell, the first step is transcription, the synthesis of mRNAs for translation into protein. Not all DNA viral genomes are ready for transcription and must be converted into dsDNA. In this lecture, we discuss DNA dependent RNA polymerase, regulation of transcription by viral proteins, positive feedback loops and transcriptional cascades, and RNA processing, the addition of 5'-cap, poly(A) tail, splicing, and RNA export.

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Dr Vinny, From Singapore where we are fighting nCoV 2019. Where are your lectures on this? Hopeful, Singapore