Plague Inc: The Cure - Bio Weapon Mega-Brutal Guide

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The bio-weapon is the very embodiment of Mega Brutal. Even with the best possible strategy, the margin for error is extremely slim. You will have to restart again and again and again... so you might as well keep restarting until you get the perfect setup to give yourself a fighting chance. Find the ideal start, save your game, lockdown that plague, and keep your authority up with everything you've got. This is the final push.

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No copyright infringement intended. Plague Inc: Evolved copyright is owned by their respective owners which includes but is not limited to Ndemic Creations. I did not make the game (or assets) and do not claim to. I do claim recording the video and audio associated with this playthrough.

Music credit:

"Shake Down"
by Gavin Luke

#plagueinc
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Taking "you're going to Brazil" to a whole new level

airank
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Bacteria cure mode day 1: ok lets explore some countries
Bio Weapon cure mode day 1: *D E C L A R E A R M A G E D D O N*

leafbou
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"Some of you may die, but that is a sacrifice I am willing to make."

- Bio Weapon Mega Brutal in a nutshell

elliotflores
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bacteria: hey, this isnt so bad
bio-weapon: THIS IS AN EXERCISE IN DESPAIR AND SELF-LOATHING

snaukball
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Field Operatives on Bio Weapon Mega Brutal be like:
"You are being rescued,
*please do not resist."*

secondblackjack
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Field Operative: "I'm gonna cure you with the power of modern Medicine and this gun I was handed".

bulldowozer
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"Bio Weapon is hard and will kill us all!"

Greenland: "Oh no! Anyways."

AWildRaito
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Imagine. You are just sitting in a cafe or something when a bunch of guys in hazmat suits walk in, saying: " Is This the guy?" "Affirmative." and then they unpack the FLAMENWERFER.

youdontneedtoknowwhoiam
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Diseases in plague inc: Om nmo I’m gomna kilm my hostsm

Diseases in cure inc: LMAO get a load of this dude clicking 5.23 / 10^52846 seconds too late.

photophone
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Person infected with bio weapon after extreme measures goes live: "hey uh doc...why did that temperature gun just rack a 9mm round?"

emerald_lord
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Pravus: *Kills the half of the south america*

Replay: *AMERICA DELETUS*

AdvanAviantoy
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"Did you do it?"

"What did it cost?"
"Half of South America Population"

lookingforabettername
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Bioweapon: Why do I hear Boss music?
*And it isn't mine?!*

adamxue
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Well, if Pravus lost his mind while trying to complete this, I think it's safe to say that if we ever get hit with bio weapon in real life, we'll all die.

velocilevon
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HE DOESNT MISS
10AM FOR A WEEK STRAIGHT
HE DOES NOT MISS
ENJOY YOUR BREAK, GOOD SIR!

jackkaczmarski
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The bio weapon as a boss: "The only way to win is let South America die."

Bio weapon when you play as it: Herp de derp I'ma kill myself if you don't stop me.

Edit: fixed

jakksonkobalt
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I love how normally he's so confident about everything, even the Shadow Plague (which I thought was immensely difficult), and then there's this where he just goes full rage mode about how hard this plague is.

WindowsMalfunction
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*"Congratulations by killing 17 people, we just saved the entire population of United Kingdom. I'm a hero, I know."*
I don't know why, but hearing that in the middle of pandemic is even funnier xD

Ah yes, unfair bioweapon vs unfair save scumming method. _Perfectly balanced as all things should be_

-Raylight
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His mega brutal run: 3/4 a billion
My casual run: 6.75 billion

Seriously. This dude is extreme

theeclipsemaster
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Plague Inc. Evolved: the one game where you're the villain, even if you're fighting a disease.

matthewentwistle