Pharmacology - Diabetes Medication

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[abbyjackson]

*My daughter drinks lots of water and urinates with the same rate, there are no other symptoms to show if those have anything to do with diabetes. This is a good information that I have gone through **Diabets.Care** She is 2 years 9 months, hale and healthy, have not done any blood test. But I am not certain if one can get diabetes at such a tender age. Please I will like to know more on that*

[tonksndante]

dude you are literally passing my meds exam for me. Thank you so much. Your videos are wonderful and you must be incredibly clever to put all this together. ♡ 😊

[filipavalente]

Hi ! Great video as you always do, however you are missing 2 very important classes of drugs for type 2 diabetes: DPP4 inhibitors and SGLT2 inhibitors. Although both classes are newer than the ones presented they are widely used by now. Thanks!

[idokoonyinyechi]

Thanks so much ...u made it easier for me ..i was scared in class when it was introduced ...but am happy now that i was able to understand it well through ur video

[jasmineken]

Nice video, I diagnosed with T1 and use the FreeStyle Libre sensor with Blucon transmitter, I track blood glucose readings on watch and phone constantly and the phone beeps at night when the glucose is out of range.

[dockg]

using this as a jump off point to familiarize myself before reading the books. thanks!

[thomaslau]

Excellent quick drawing. Good explanation and learn fast.

[jpm]

You make really great videos man !
real big fan
your content needs more recognition
love form india !

[Uzair]

Great Video again, but you forgot 1 antidiabetic class which is abit new and really different, gliflozin class, eg canagliflozin.. it acts on PCT and block reabsorption of glucose from kidneys so no or less glucose is reabsorped=> decreases blood sugar.. its contraindicated in kidney diseases/failure

[celineait]

rhank you very much you're the best teacher i had ever seen even if i don't understand english very much but all your videos are helpful thank you very much

[patelmeet]

The anti diabetic medication which cause the increase production of the insulin, But definition told that type two diabetes mellitus is caused by insulin resistance so what the meaning of giving that medication

[meedok]

Nice presentation
But you forgot DPP4 inhibitors
(Sitagliptin, saxagliptin, vildagliptin ).
SGLT2 inhibitors
And
Meglitinide derivatives.

[salimahmad]

Your endless compassion towards humanity Dr Ogie has broader my heart, I never wanted to have a surgery and prove all the doctors here that they were wrong and I really didn't know what else t do than believe in your medicine, thanks so much for curing my type two diabetes

[MikeB-spgp]

Hi Armando.

Huge fan here-- but I think you made a couple errors here that are significant enough so you may want to re-record the audio at the beginning:

1. Hepatic glucose transport is not insulin-dependent. I believe the liver has GLUT2 channels, that allow for diffusion of glucose without insulin. You're right, skeletal muscles have GLUT4 channels, that require insulin to emplace them in the cell membrane. The other main locations of GLUT4 channels are in adipose tissue. I believe the heart also has some GLUT4 channels.

2. You're right that metformin inhibits hepatic glycogenolysis-- It also inhibits hepatic gluconeogenesis. Those actions in the liver are the primary a1c-lowering actions of metformin. Metformin might also increases insulin sensitivity and slow gastric emptying-- but whether these actions are significant enough to lower blood sugar is open to question.

3. Metformin will reduce A1c about 0.5%, and promote weight loss of 3-5 pounds. Neither of these modest benefits offer its clinical main benefit. The major benefits of metformin are cardiovascular and longevity. Metformin reduces risks for myocardial infarction, stroke, kidney failure and cancer. It also confers an increased life expectancy of as much as 4 years for people with diabetes (though not for people without DM-- a big disappointment for pharma, who thought they might have had a 'fountain of youth' drug on their hands.)

Again, Armando, I'm a huge fan of yours. I've been using your videos, on a regular basis, for years. But nobody's perfect. You may want to take a look at this stuff.

[carlalee]

Thanks for the great lecture. Just a Q... you haven't covered DDP-4 inhibitors and SGLT-2 inhibitors in this lecture. Is there any other lecture that covers these?

[sadin]

Very nicely presented...However, where is DPP4 inhibitors and SGLT2 inhibitors?

[tecvideospro]

I am huge fan of yours bro. helped me a lot in my studies.

[mabondavis]

hello, very informative video. my cousin was also suffering from this condition. he visited many hospitals but no one cures this disease. one day he visited planet ayurveda and they gave him a diabetes care pack. now he is fit and fine.

[louiethemouseful]

Why do you say "inSHUlin?"...

[deepikaaggarwal]

That was really helpful lecture 😃
Thank you so much 😊