Fate of pyruvate

Lecture on Fate of pyruvate.
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The overall process of glycolysis is:

glucose + 2 NAD+ + 2 ADP + 2 Pi → 2 pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O

If glycolysis were to continue indefinitely, all of the NAD+ would be used up, and glycolysis would stop. To allow glycolysis to continue, organisms must be able to oxidize NADH back to NAD+.
Fermentation

One method of doing this is to simply have the pyruvate do the oxidation; in this process, the pyruvate is converted to lactate (the conjugate base of lactic acid) in a process called lactic acid fermentation:

pyruvate + NADH + H+ → lactate + NAD+

This process occurs in the bacteria involved in making yogurt (the lactic acid causes the milk to curdle). This process also occurs in animals under hypoxic (or partially anaerobic) conditions, found, for example, in overworked muscles that are starved of oxygen, or in infarcted heart muscle cells. In many tissues, this is a cellular last resort for energy; most animal tissue cannot tolerate anaerobic conditions for an extended period of time.

Some organisms, such as yeast, convert NADH back to NAD+ in a process called ethanol fermentation. In this process, the pyruvate is converted first to acetaldehyde and carbon dioxide, then to ethanol.

Lactic acid fermentation and ethanol fermentation can occur in the absence of oxygen. This anaerobic fermentation allows many single-cell organisms to use glycolysis as their only energy source. Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia.

[tasneembaloch]

Tomorrow is my biochemistry paper and this topic is a part of my topic thanks sir it helps me to much

[merlinjohn]

One of the simplest explaination I ever heard …

[ashikuzzamanbiswas]

Thanks alot.your presentation very good.

[devicejason]

itz simple and well explained ...thanks

[NostocFc]

What is the fate of pyruvate produced during glycolysis in muscle ???
Pls answer this question

[nigelguy]

actually fatigue is caused by accumulation of inorganic phosphate from the creatine kinase reaction and not from the accumulation of lactic acid

[FarazaliAli-oe]

Bhai Urdu mein lecture diya kro Kuch samjh ni lag rhi 😢😢