Molecular Biology #1 2020

A typical animal cell contains more than 40,000 different kinds of molecules. In the past 20 years, great progress has been made in understanding how these molecules combine and interact to form a living creature.

Prof. Emeritus Barry Bowman organizes the course and offers two lectures. Two other professors from the Molecular, Cell and Developmental Biology Department at UCSC present lectures covering topics related to their research programs.

These talks are intended for a general audience. A scientific background or knowledge of biology is not expected. Barry Bowman, the course coordinator, will begin with a basic review of genes, proteins and cells.

Lecture #1. Prof. Emeritus Barry Bowman: An introduction to the basics of molecular biology
Lecture #2. Assistant Prof Josh Arribere: How quality control protects our cells
Lecture #3. Prof. Martha Zuniga: SARS Wars: Immune defenses against SARS-CoV-2 and COVID-19 pathology
Lecture #4. Prof. Emeritus Barry Bowman: Digging deeper into DNA

Barry Bowman is Professor Emeritus of Molecular, Cell and Developmental Biology at UCSC.

[wackymontederamos]

This lecture made my life so much less boring.
I worked as a household helper here in Singapore, all the house chores is choking me to death until I become interested into biology. Now i can cook, clean and iron so much better while listening to this lecture.

[jessefranklin-peiper]

glad that there are professors like this out there, not just pumping out information, but rather taking their time to be sure their students understand the material. So patient!

[jjordanbaird]

The question answered at 14:18 is excellent. It’s cool that you can find lectures and talks like this on the Tube

[VidaxTheDragonMage]

This has been, and will be so valuable to me in my career. Thank you so much for making this publicly available!

[alanlee]

Excellent presentation which explains complex problems in a simple way. The coherence of the whole talk is so good that I enjoyed every second of the talk. Thank you!

[glendaoliveira]

Thank you for the awesome lecture! I'm a Ph.D. student, with chemistry as a background, adventuring myself in the biochemistry field. This lecture literally changed my way of understanding the basic concepts!

[tylermarshall]

What a badass lecture. Great work, cheers and be well!

[marksilver]

Such a complicated structure couldn't just happen by chance, nature itself is pure intelligence, and it boggles the mind!

[rodneyspence]

I’ve been watching the Ken Burns documentary called “Cancer - The Emperor of All Maladies” in which they say most types of cancer involve mutations on 50-100 different genes whereas at first they thought it only involved a few. And even for those types that do just involve a few genes the cancer will keep mutating to resist the drugs. I hope some of the young people here keep learning about the cell biology so that this nightmare of a disease can be defeated. Thanks for teaching this important information in an understandable way!

[RollingTree]

Excellent! Explanations laying out in orderly, contextually thorough fashion what physically/visually happens, and why, via layman descriptions, before adding terminology. Rare. So often, teaching begins with, and emphasizes, terminology and abstractions, and fails to clearly link processes. Thank you!

[markoconnell]

So the code to make the protein which it binds to on the DNA to start is from the DNA to begin with. This is why the topoisomerase so important so a factor can get to the binding spot it is programmed for on a molecular level. Brilliant method. Thank you to whomever discovered this.

[lugus]

1:22:35 this is an interesting question because "purpose" and "function" are words we see all the time in biology in explanations for why something is the way it is, but you don't see that in other sciences as often. A geologist isn't going to tell you purpose or function of why a rock exists, just how

[Not-iphn]

A profound lesson on the introductory of Molecular biology, the fundamentals are truly astonishing you made a rather complex lesson turn into a simple explanation of the functions of cells to a whole new level.

[NRd]

Very informative right off the bat. The slides really helped along with the presentation. Thank you for taking the time to create these videos and inform the public on such interesting and important subjects.

[_neophyte]

33:00 this is so fascinating. it looks like machine code, like binary code (obiously it's not truly "binary" but you get the point). Our bodies are truly just machines, the most marvellous machines to ever exist. I'm going to start my degree in biomedical engineering soon because of the fascination i have for nature and the desire to contribute to people's health using technology.

[zaidgamer]

You are amazing what a very informative lecture

[maharlikawarrior]

Topic is well-explained...thank you this video

[markoconnell]

How does the binding factor know the correct spot to bind to the DNA? Why that spot versus any and every other spot on the DNA of the bacteria trying to get the sugar molecule?

[ezzovonachalm]

could I have had the opportunity to see this very presentation as I was a medicine student

[kainajones]

Great lesson. Would be good if your cursor were a bit more prominent . Hard to know where your pointing sometimes