Label-free live cell imaging of glioblastoma cells undergoing autophagy

A𝐮𝐭𝐨𝐩𝐡𝐚𝐠𝐲: 𝐚 𝐛𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐩𝐫𝐨𝐜𝐞𝐬𝐬 𝐨𝐟 𝐜𝐞𝐥𝐥 𝐝𝐞𝐚𝐭𝐡 𝐨𝐫 𝐜𝐞𝐥𝐥 𝐬𝐮𝐫𝐯𝐢𝐯𝐚𝐥?

Autophagy is a cellular process essential for the maintenance of cellular homeostasis that involves the degradation and recycling of damaged organelles, proteins and other cellular components. Excessive autophagy can lead to cell death whereas dysregulation of it can be implicated in various diseases, including Alzheimer's and Parkinson's disease, or can even promote cancer cell survival.

This video captures glioblastoma cells undergoing autophagy upon drug induction.

At Nanolive, our label-free technology provides unique insights into the dynamic process of autophagy, capturing key steps such as engulfment of cytoplasmic materials, increase in vacuolation, organelle degradation, cell shrinking and cell to cell interactions. Understanding the dual role of autophagy in health and disease can help in the development of more targeted therapeutic strategies.

[ronaldcardoso]

These are amazing videos. Unfortunately I don’t think the majority of people appreciate what they are watching but hopefully their children and grandchildren reap the knowledge and understanding of this phenomenon.

[KathySipkema]

Awesome Science to observe this with my eyes 👀!! amazing!
Technology. Photography.
So much beyond my comprehension…..
Thank you so very, very much!!

[GraemeWight-wxxz]

These are my new goldfish to watch when i want to relax 😊

[ricodacanay]

Is this on a slide? How is he capturing these images? Can someone explain?

[HotSeat]

I love these videos! I share them with the nursing and doctor students in my family. I just told them to subscribe! ❤️❤️❤️🫶🇺🇲