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Glycolysis | Cell Metabolism Part 1 | Macronutrients Lecture 17
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This video is part 1 of the Cell Metabolism module within a lecture series on the nutrition science of macronutrients.
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Lecture Development, Hosting & Post-Production by Lara Hyde, PhD
Video Production by Robbie Hyde
The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this video is for general information purposes only.
References
Chapter 9 Wardlaw’s Perspectives in Nutrition, 2019 (Editors: Byrd-Bredbenner, Moe, Berning and Kelley, 11th edition)
Remember that lysis means to break apart, so glycolysis is a breaking down pathway. Glycolysis goes through a series of reactions in the cytosol to break down glucose into two 3-carbon pyruvates. In the process, it reduces some NAD to NADH - this is typical of catabolic redox reactions. These reactions require an investment of ATP but also make some ATP, so you get a net gain of 2 ATPs through glycolysis. The three carbon pyruvate goes through a reaction where it loses a carbon as CO2 to make a 2-carbon acetyl group, which gets added to CoA to make acetylCoA. AcetylCoA enters the mitochondrial matrix.
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