Proton Pump Inhibitors and B12 Deficiency #b12deficiency #digestivehealth

Are you taking proton pump inhibitors (PPIs) for acid reflux, indigestion, or other digestive issues?
In this video we're going to look at the impact of proton pump inhibitors on vitamin B12 deficiency, how it comes about, how prevalent it is, how long you need to take PPIs in order for this to happen, and other things you should be looking at with regard to proton pump inhibitors and vitamin B12 deficiency.

This video, we want to look at proton pump inhibitors (PPIs) and vitamin B12 deficiency. PPIs are a class of medications used to treat gastroesophageal reflux disease (GERD) and other conditions that involve too much stomach acid. They work by blocking the production of stomach acid, which can in some cases help relieve symptoms such as heartburn, reflux, nausea, and burning in the stomach and esophagus.

While there are some benefits to PPIs, they do come with costs. One of the costs is a reduction in the body's ability to break down and absorb certain foods and nutrients, including vitamin B12. Vitamin B12 is an essential nutrient that is important for various functions in the body, including red blood cell production, nerve function, and even DNA synthesis.

Vitamin B12 is absorbed in the small intestine, but in order for it to be absorbed, you need enough intrinsic factor. Intrinsic factor is a protein produced in the stomach that helps to bind to vitamin B12 and facilitate its absorption. PPIs reduce the amount of stomach acid, which also reduces the production of intrinsic factor. This can lead to a decrease in vitamin B12 absorption.

The amount of vitamin B12 absorption that is decreased depends on which PPI you are taking and the dose. Generally speaking, PPIs reduce the amount of hydrochloric acid by 60 to 80%.
A study published in the Journal of Gastroenterology in 2010 found that people who took PPIs for two years or more were more likely to have low levels of vitamin B12 than people who did not take PPIs. The risk for vitamin B12 deficiency was even higher in people over the age of 65.

[SBrenno-xt]

Hello doctor, I’ve been admitted into the hospital with low electrolytes, low potassium, and sodium, and abnormal bowel X-ray, my B1 serum test came back abnormal today, abnormally High at 159 nmol/L the normal range is saying 78-143 and the b12 was 1342. What do you think the key component of this case could be? … I’ve had chest pain and fatigue is way through the roof. Am at the point of muscles stuck in contraction… and blue lips… breathless, and can’t function. Medical doctors have accepted it’s a functional case, but are left scratching their heads to what to do with me. … I’ve left my book at home wich I’ll have a family member bring to me tomorrow, am in uk 🇬🇧 and feel like I’m close to death, 💀 any output advice from you or anyone out there reading this, please help, god bless you doctor for your continuous support and hard work in making this information accessible. And sharing your valuable knowledge with the world. … sending you lots of ❤️ THANK YOU 🙏 X