Vitamin B3 Niacin Deficiency (Pellagra) | Sources, Causes, Symptoms, Diagnosis, Treatment

Vitamin B3 Niacin Deficiency (Pellagra) | Sources, Causes, Symptoms, Diagnosis, Treatment

**PLEASE NOTE THE FOLLOWING ERRORS:**
1) When I said, "niacin is also known as nicotinic acid or nicotinamide", this is incorrect - niacin IS also known as nicotinic acid, but nicotinamide is another form of vitamin B3. Vitamin B3 comes in THREE forms: Niacin (also known as nicotinic acid), nicotinamide (also known as niacinamide), and nicotinamide riboside.
2) When I said NADP is generated in the pentose phosphate pathway, I meant to say "NADPH" is generated in the pentose phosphate pathway.
3) Pellagra is a condition CAUSED BY NIACIN DEFICIENCY, not necessarily another term for Niacin deficiency
***Sorry for the confusion***

Welcome to another lesson in the Vitamin B series!

Vitamin B3 (Niacin) is a water soluble vitamin required for nutrient metabolism and synthesis of fatty acids and cholesterol. Niacin is acquired from dietary sources and via endogenous synthesis in the liver. In this lesson, we discuss the dietary sources of niacin, recommended daily intake, absorption/excretion, causes, signs and symptoms of Pellagra (condition caused by deficiency of niacin), diagnosis and treatment.

If you found this lesson helpful, please like and subscribe to help support this channel.

JJ

-------------------------------------------------------------------------------------------------------------

EXCLAIMER: The content used in this lesson is used in accordance with Fair Use laws and is intended for educational purposes only.

**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for EDUCATIONAL PURPOSES ONLY, and information presented here is NOT TO BE USED as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

-------------------------------------------------------------------------------------------------------------
For books and more information on these topics

Check out the best tool to help grow your YouTube channel (it’s helped me!)

-------------------------------------------------------------------------------------------------------------

Check out some of my other lessons.

Medical Terminology - The Basics - Lesson 1:

Infectious Disease Playlist

Dermatology Playlist

Pharmacology Playlist

Hematology Playlist

Rheumatology Playlist

Endocrinology Playlist

Nephrology Playlist

---------------------------------------------------------------------------------------

*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*

[jjmedicine]

**PLEASE NOTE THE FOLLOWING ERRORS:**
1) When I said NADP is generated in the pentose phosphate pathway, I meant to say "NADPH" is generated in the pentose phosphate pathway.
2) Pellagra is a condition CAUSED BY NIACIN DEFICIENCY, not necessarily another term for Niacin deficiency
***Sorry for the confusion***

[ranicefreire]

Recommended daily dose are away to low...only see benefits with much higher dose

[Psychiatry.]

Most symptoms are identical to Schizophrenia, even some schizophrenic patients does not flush even after taking 5, 000 mg daily of Niacin (Nicotinic Acid).

[Kittiesanddragons]

So this one time i was asked a question of 4Ds of Pellagra, i told Dementia, Diarrhoea and Dermatitis but couldn’t remember the 4th. The teacher looked me dead in the eyes and said Death. Lmao that cracked me up

[RS-puti]

Very well explained, thank you for sharing ✌️

[anny]

Love the lessons..
My friend has the red irritated hands up to the wrist.. like wearing red bumpy looking gloves.. happens every early fall through late spring
So strange.. she doesnt have the other symptoms unless its super mild

[pramujisinggihriyanto]

Very helpful information.
Many thanks, Dude

[SkedgySky]

I get a mild flush starting at 50mg. ... A crushed tablet = super fast absorption. Usually a hot tingly sensation around my lower face, is my first sign. Very interesting.

[ilciavargas]

Interesting video! yes legumes also contribute to our good health as legumes provide vitamins, minerals and legumes ocxigenate the blood given a lot of energy to people. I consume legumes 5 times per week. I keep slim and I do have so much energy just like a young person¿ we are what we eat so this is why I have a natural food! No sugar, not frying food, no proced food and no sugary drinks, just water and home made food. You can make a pot of legumes that will last 4 days without been frozen and warm up in the cooker no in the microwave.

[FisherKot]

I take 3, 000mg of niacin a day. I love the flush. I’ll never stop

[gregorykarimian]

Tryptophan makes quinolinic acid which makes nad. Tryptophan does not make niacin.

And let me add by saying why this is important. It’s because isoniazid inhibit the production of b3 via the tryptophan pathway. That is why you can supplement the patient with niacin because they’re two different pathways.

[karunasree]

It helped but
If given % of b3 in food items it is more helpfull good thanks

[Happy-jvfd]

Can you use Niacinamide orally in the powder formula ?

[thokalaramesh]

Tq, i understood about the pellagra disease and wt is NADPH

[nitinnaik]

Property explained. Please share the prescription drug name

[CyrilAndPriscilla]

Hepatic synthesis also requires B6, not just riboflavin.

[kh]

Niacin supplements in high doses ( capsules and tablets )may induce insulin resistance !

[hvvijuka]

hi Doc, hypothyroid people do not flush when they take immediate release niacin, what's the reason?

[letmeintoyoursoul]

Vegan diets are not innately an issue if properly balanced and centered around eating whole foods . Malnutrition is the issue because you can eat an inadequate omnivorous diet and run into a B3 deficiency. I think isolating certain vegan diets creates a sense that this diet is more prone to this deficiency when the matter at hand is just poor nutrient intake of niacin. Furthermore if one is eating a variety of grains, legumes and fruit then they should be able to easily meet their needs even with men who have a slightly higher RDA of 16 mg/day.

[majesticbutterfly]

Can someone with a fatty liver take niacin without making the liver worst???😮