Genes hiding among the junk: The Dark Proteome

Even though it was completed a quarter century ago, geneticists still struggle to estimate the number of genes in the human genome. They went from ‘hundreds of thousands’ to “22 thousand”, then more recently to “about 19,500”. The number, however, has just exploded. Tens of thousands of new genes with important functions were discovered hiding in the ‘junk DNA’. Dr Rob explains what these new findings mean to the creation-evolution debate.

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[owlfethurz]

Important information to build upon. Praise the Lord! Let the whole earth be filled with His Glory!

[anthonypolonkay]

Absolutly cool progress to the sure. May come as a surprise to those who think we evolve, but to those who think we are purpousfully created it is what's to be expected.

[JungleJargon]

Thanks for your work and dedication Dr. Carter!

[annhinz]

Very interesting. Reminds me of the verse that says it is the Lord who conceals and the joy of kings to discover. Obviously, paraphrased.

[yanfeili]

wow, this is really interesting and groudbreaking!

[zzzzz]

So the evolution theory is now SLOWING scientific progression... oh the irony.

[kenfunk]

Thanks, you closing comments made me appreciate the idea of a CIB even more.

[stuartwendywithrington]

Thanks Dr. Carter, really appreciated you sharing about the tech you used.

[JK-trmt]

Could you do a presentation on ORFan genes? And those who criticise creationists over it (from the long non-coding seekers). I'd like to hear your take on this. Thanks.

[yanfeili]

Dr. Carter, if you can translate a gene by eyeballing it, by definition, you must be a ribosome... lol

[watchman]

If they believe it's junk, why would they look for it?

Could someone make a film showing how they take a sample, get a sequence, and then turn that into digital data?

[hglundahl]

// if there's a mutation in 7:31 there that like deletes a single letter 7:33 or adds two letters you have what's 7:35 called a frame shift mutation and a 7:37 frame shift usually destroys the protein 7:39 because as soon as you shift out of 7:41 frame you're into random territory and 7:43 it's only going to be probably maybe 20 7:45 codons later before you get a stop 7:47 codon //

So, frame shift mutations are NOT a very probable source of new information, I presume?

[sabhishek]

Dr Carter, I am a layman and I just want to understand about the brie cheese video. Can Horizontal Gene Transfer rescue brie cheese? Asexual organisms like Cyanobacteria reproduces asexually but they have horizontal gene transfer. Can HGT rescue asexual organisms like Cyanobacteria that do not have any sexual ancestors and have reportedly lived atleast 2.5 billion years ago from the situation that Brie cheese is in?

[lighthousenetwork.tv-media]

bro used to Cook by reading DNA like an Enzyme with his eyes

[smartass]

What about all the genes on the y chromosome ? a korean test with blind folds and blue light and electromagetic feilds finds only men in those conditions have enhanced sense

[AdamosDad]

Genesis 1:1In the beginning God created the heavens and the earth. 2Now the earth was formless and void, and darkness was over the surface of the deep. And the Spirit of God was hovering over the surface of the waters.…Colossians 1:16-17
For in Him all things were created, things in heaven and on earth, visible and invisible, whether thrones or dominions or rulers or authorities. All things were created through Him and for Him. / He is before all things, and in Him all things hold together.

[kurtdejgaard]

So here's a classic example of people lecturing other people without actually understanding what they're talking about. It seems to be "so long as the others don't know better, I can claim whatever I like".
Quote (0:55): "Different cell types will produce similar proteins as another cell type. But there'll be pieces that are different, because they can rearrange parts of the gene as the proteins are getting made".
Answer: But that's not how "alternative splicing" works. It doesn't "move things around". It can cut things out or leave them in. It can't "move things around".
Quote (10:05): "What they did, was took the ribosomes and they froze them in place, as they were grabbing onto an RNA. And then they sequenced all of the RNAs that were associated with a ribosome. In other words the thing that was doing the translation into a protein. And they were shocked. They found - no joke - tens of thousands of new genes".
Answer: That doesn't mean they are coding for anything. That actually has to be proven, first. So this in itself is not a proof of tens of thousands of new genes.
More importantly: What was the source from which the ribosomes were harvested? The question is legit, because we know cancer cells mess around with their DNA - the repeat some parts - they throw away some parts - they hypermutate some parts - they rearrange some parts. -They often end up with what is called "aneuploid" DNA, where we can barely recognize the chromosomes, because everything is messed up. That, however, does NOT make that mess "new genes". It is just that: A mess. A mess that may play into the severity of the underlying cancer. But a more or less random mess, non the less.
Quote (12:05): "Initially there was not enough protein coding genes in the genome".
Answer: According to what logic? How few or how many is "not enough"? The statement is nonsensical.
Quote (12:15): "And now we have doubled or maybe tripled [...]"
Answer: We don't know that, either.