The $1 Billion Obesity Pill That’s NOT a GLP 1

Novo Nordisk's Billion-Dollar Obesity Drugs, Semaglutide Study, and GLP-1 Impact

In this episode of Downsized News, hosts Laraine and Christopher Durham discuss the latest developments in the GLP-1 medications and obesity treatment space. Key topics include Novo Nordisk's billion-dollar deal with Lexicon Pharmaceuticals for the new non-GLP-1 obesity pill LX 9851 and its potential game-changing impact. They also talk about a new study on the Semaglutide pill showing it can reduce heart attack and stroke risks by 14% in type 2 diabetes patients. The episode reveals how GLP-1s are driving up drug costs and contributing to the decline of weight loss giants like Medifast. Other highlights include the rise of oral GLP-1 drugs, a partnership between Collective Health and Noom to make these medications more accessible, and data from Deloitte showing the massive impact of GLP-1 drugs on the pharmaceutical industry. The hosts emphasize the importance of consulting healthcare professionals and being cautious about the high costs of these medications. They end by highlighting their store and thanking their members for their support.

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00:00 Introduction and Overview
01:19 Novo Nordisk's Billion Dollar Deal
04:50 The SOUL Trial: Oral Semaglutide
07:45 Impact of GLP-1 Drugs on Drug Costs
11:51 Medifast's Struggles in the GLP-1 Era
15:17 Rani Therapeutics' New Oral Obesity Medication
17:56 Collective Health and Noom Partnership
20:00 Deloitte Report on GLP-1 Drugs
24:23 Conclusion and Sign Off

[deniseirby]

Starting week 14 and still on 2.5mg Zepbound. Down 28.8 lbs and feeling great!

[DianaLynn]

I hate Optavia, it needs to be shut down completely! Have a friend who went on it a few yrs ago. She was only allowed to eat about 800-1000 calories a day total. She was always weak and looked like she was starving to death and gaunt. But she did lose over 100 lbs in about a yr, lol. She has now gained a lot back and eats like she did before she went on it. I think she was starving so badly that her body now wants her to feed it even more to make up for it!!
Also know another acquaintance who lost a lot on it and gained it all back, plus some, VERY quickly when she went off of it. Both ladies' metabolism are now really messed up from it 🤦‍♀️😬

[drhnsd]

Your video editing is top notch! Enjoyed the show - thanks.

[C.MarieAdams]

Very valuable information! Thanks for keeping us informed! I'm week 5...Zepbound 2.5mg down 11.5 lb

[Nao.miedits]

The content is exceptional! ❤ Thank you.
Securing an interview with a pediatrician specializing in adolescent health to discuss the use of GLP-1 medications in teenagers would be highly beneficial.
Looking forward to your content every day ❤

[odysseyscots]

Really great, well researched information. thank you!

[valerieSMITH-le]

Thanks for the news, look forward to it every week!

[sueblue]

I did noom also. I did alot of things too! 😊

[augusthome]

If there’s competition it should bring the cost of GLP 1 down.

[AdventuresInStyling]

That was ALOT of news! Thanks for gathering and reporting all that. Yup I could only handle Medifast for a week or two and then with a shrunk stomach, some results, and determination I could eat less and healthy..get 14-22 lbs off then always gained it back. So glad those days are over!

[Kouloves-]

My friend sister signed me up for Optavia, I received my ordered, tried it for two weeks and I couldn’t keep up. I am so glad, I don’t have to try anymore new diet.😂😂😂

Thank you for the updates.

[krickenthekraken]

Wow, that was awesome guys! One of the best yet! Keep bringing that news! Although honestly, could we have some better news? Like some deep price cuts for those of us that pay out-of-pocket!

[KieranGetsFit]

Very interesting! Great news update. Novo seems to be spending big for the future, which is only good news in my opinion for everyone.

[MariaMurphy-lv]

Wow ! That’s a lot of great information 👌

[weighitoutwithalexis]

Another great commentary💚 FYI I like the shot if it aint broke why should I fix it

[RobertB-wj]

Thank you for these!
Has anyone received a shipment from Mochi?

[ChrisQuilts]

I always find your in the news segment informative and interesting. Have you heard any news updates on the current clinical trials for the medication from Viking Therapeutics? I have read they are working on oral as well as injection based obesity medications. The more that come to the party makes me hopeful the prices will come down, but with Novo buying up competitors I see that as negatively impacting the market as well.

[djbosnick]

The same EverNorth that owns Express Scripts? Interesting info. Thank you!

[jazzymdg]

Thank you for the news...it's all a big money game

[resamckinney]

Laraine, love you repping your Duke blue shirt!