Cell Division Time lapse

Time_lapse of cell division from second cleavage. The animal pole is clearly visible in the upper half of the image.

A brief note about the image capture techniques:

Hi I can say that it was done with a custom designed microscope based on the "infinity optical design" It is not available by any manufacturer. I built it. I used LEDs and relevant optics to light the egg. They too were custom designed by me. The whole microscope sits on anti-vibration table. I have to say that it doesn't matter too much what microscope people use to perform this. There are countless other variables involved in performing this tricky shot, such as for example: the ambient temperature during shooting; the time at which the eggs were collected; the handling skills of the operator; the type of water used; lenses; quality of camera etc etc. Hope this helps.

[Thereisnospn]

At first I thought this was an animation. It's the first time I see this in such detail. Fascinating how the divisions move in waves through the egg.

[clearevil]

Needs a time lapse counter to see how much time it actually takes.

[Ohmriginal]

I love how each cell manages to divide at nearly the same time as the others

[joseluisbenitez]

This is one of the most awesome and underrated video I've ever seen. I've sent it to every friend of mine but few people is able to apreciate it's beauty.

[jsandroid]

Great job on getting this footage and sharing it with everyone @francischeefilms! I really appreciate the effort and I'm happy I get to witness this amazing process

[PSCLKL]

Why are there always some people who dislike something as astonishing as this? Humanity doesn´t need this kind of negativity ;)
Great video!

[theyoutubechannel]

Awesome !!!! One of the best youtube video for me ! Thank's you so much !

[jb_]

Fascinating. Hats-off to you for your custom setup build, looks like a 3D render... amazing!

[RecBrwn]

Great channel. Subscribed. Hope you get the recognition you deserve for this.

[muggsylauer]

Incredible video! And yet, as of this post, there were three people who hated it enough to give it a "thumbs down." I just don't understand people.

[betulcimenay]

Wow i thought this was animated at first!!! Amazing work dude.

[anglemili]

Such a great footage! Cant stop watching it.

[SingingXavier]

Ok - for all those doubters here.  I have known Francis for 25 years, I have seen his set-up and discussed his microscope, lighting and lensing design over years.  He was a scientist and professional microscopist in his past career, and he has been working on this for years.This is 100% real.  Congratulations.I can also confirm that CGI at this Level is way beyond him!! Hahaha

[dano]

This is absolutely one of the most fascinating things I've ever seen.

[michaelpaulsen]

What imaging modality (light microscopy, macro lens, etc?) are you using to film this?

[ThinkingAtheos]

Do you have behind the scenes photo/video or a photo of your microscope setup?

[lsdinc]

love this! I want more!! I work in Medical animation. This is really lovely :)

[MyanmarWildWaters]

Is there a possible way to have a time lapse from the single egg cell to a tadpole that's ready to hatch?

[greeches]

Fantastic, would LOVE to know more technical details! Well done

[olivermewes]

Amazing! this is so stunning! thanks for uploading! i would be happy if i can use this in my dipolma project :)