Aneuploidy via Telomere Attrition

Telomere dysfunction and aneuploidy are both common features of cancer cells. But are they causally linked? Watch and listen as Titia de Lange and Teresa Davoli take you on a brief, personalized tour of their findings on how the persistent DNA damage signal incurred by dysfunctional telomeres leads to tetraploid and, ultimately, aneuploid cells.