Hans Selye's General Adaption Syndrome and the HPA Axis: Exploring the Connection

Dr. Hans Selye first described General Adaptation Syndrome in 1950 with three stages that act as a guide to assist healthcare professionals with their evaluation and early intervention strategies. Although clinically defined in stages, Dr. Selye cautioned that General Adaptation Syndrome rarely occurs in a pure form. It’s complicated by underlying actions of the stressors, so is really better defined as a spectrum. This spectrum, and our central system response to it, is referred to as the hypothalamic-pituitary-adrenal or HPA Axis. Explore the connection between General Adaptation Syndrome and the HPA Axis further.