Can miRNAs be used as aging biomarkers?

What are miRNAs and can they be used as biomarkers for aging?

TIMESTAMPS;
Intro - 00:00
What are miRNAs - 00:58
How they change during aging - 03:40
Effective biomarker? - 06:56
NMN study and tissue specific biomarker? - 08:00

REFERENCES;

Aging Cell. 2018 Feb;17(1):e12687. doi: 10.1111/acel.12687. Epub 2017 Oct 17. **Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits**

NMN:

Geroscience. 2019 Aug;41(4):419-439. doi: 10.1007/s11357-019-00095-x. Epub 2019 Aug 28.

[odrlmc]

Wow, you keep doing it. Another amazing video! The tailoring of biomarkers is one those unintuitive things that immediately becomes intuitive once its explained to you. ...like obviously you would need do that, you're dealing with different levels of accumulation of damage in the body depending your epigenetic age.

[brucebird]

Excellent presentation as usual! Deeply grateful. You are invaluable in guiding my reading and overall understanding of the ageing process.

[beroo]

hi, i really loved your video,
I have a literature review about whether extracellular vesicle vesicles are a good biomarker of aging or not, may you advise me how I can evaluate whether Evs are a good biomarker of ageing or not, i am not sure what I need to research for and how I can discuss whether they are good biomarkers of ageing or not. Thank you

[odrlmc]

Just wondering if you'd come across the huge breakthrough Deepmind made in relation to solving protein structures and if you had any comment on it?