Oxidative Decarboxylation of Pyruvic acid

Oxidative decarboxylation of pyruvic acid:
The two molecules of pyruvic acid formed from a glucose molecule move into mitochondria and are oxidized, decarboxylated to two molecules of acetyl coenzyme A (acetyl Co~A). These 2 carbon compounds are formed by decarboxylation and dehydrogenation. This reaction is catalyzed by pyruvic dehydrogenase and two molecules of NAD+ are reduced to NADH2. During this reaction two molecules of CO2 are released. Oxidative decarboxylation of pyruvic acid occurs only under aerobic condition. Under anaerobic conditions, the pyruvic acid is reduced either to lactic acid or ethyl alcohol depending on the nature of the organism.

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[sandykim]

It was such a clear explanation. Thanks