Partition coefficients

A lecture for the University of Lincoln on partition coefficients and why they are important in drug absorption. Both LogP and LogD are explained and their relationship to pH.

A textbook based on this YouTube channel is now available. Clinical Pharmacokinetics From The Beginning (a practical approach) can be found as an e-book or paperback from Amazon.

Note that the book does not cover partition coefficients but will be of interest to those requiring knowledge of basic pharmacokinetics.

[mairaa]

This video is the only video which has actually helped me understand both coefficients P and D, thank you so much!

[mck]

This was incredibly helpful. Thank you for making this video!

[Ace]

I pay $18, 600 a semester at the University of Technology of Sydney's Graduate School of Health and instead of bothering to teach us themselves, they send us a link to your video. Hope you're getting a kickback mate

[sarahhe.]

This is the best explanation of the concept!!!! Life saver

[vitokonte]

VERY useful and clear explanation. Excellent for my pharmacy revision! More of these videos would be awesome!

[ZHEER]

Thank you very much, sir! My lecturer can't explain anything well. I'm glad I was able to find this video.

[johnblacksuperchemist]

EXCELLENT I finally understand Kc and Kd. Except one thing. Your video was great. I am going to outline this video and put it in my notes it was that good

[n.sue-ann]

Really learnt lot from watching this. Please keep them coming.

[nakulakolkar]

excellent sir, it was a visualization of mathematics in true sense

[jaskaur]

Thank you so much, I'm a pharmacy student and this has really helped me! Please make more videos! :)

[crashjohnny_]

Awesome video! Thank you so much. You explained it in a very easy way to understand, I really would like to see more videos of yours!

[goldmember]

Thanks a lot. You have made it so simple ! Amazing.

[erikavillacis]

Thank you so much. You really solve my life.

[saumilshah]

You are awesome, thankyou for your contribution.

[WheelofFortune]

Clear explanation! Thank you very much

[hayaali]

Excellent lecture ! Thank you so much !!

[johnblacksuperchemist]

...am i right in assuming Kc=Kp=Kpc are all the same thing Why does Kp / logKp not take in to account what the solute I did a problem where the Kpc for ether/water was 4. I can not remember what the solute was but let us say it was acetic acid. Is the Kpc for ether/water... where the solute is pentanoic acid ....going to ALSO be 4 Cause acetic acid is miscible in water and pentanoic is not so i would think the Kpc would be different since pentanoic acid is less soluble in water. But the equation does not seem to take that in to

[AshishKumar-hmfo]

Is there any software or online web site where we can find these values for a particular compound.

[futuredrkiran]

Brilliant, very clear in explaining Log D and LogP!!!! Thank you sir.