Homology-dependent double strand break repair

In this animation, we explore how a transposon moves as a consequence of DNA cut-and-paste transposition.

[reeseymeimei]

I will take my genetics exam and remember this man whispering about double strand break repairs.

[gingerrmoe]

Snape, you gotta move away from the microphone when you breathe.

[karstenlane]

This was incredibly helpful. To see this animation done with DNA looking structures, as oppose to just lines, made a world of difference. Thank you millions :D

[daniellaschaening]

Wow! I didn't know I could speak parseltongue, but I understood everything this guy just said!

[omrisinder]

whats going on with that man voice??
does anyone else feel discomfort with that??

[misterphuzz]

I don't care about the voice. At least I can understand the words he speaks, unlike many other big-time science video producers. And the visuals were so helpful.

[dinosaursgorawrish]

its worse because when you turn up the volume you can hear his heavy gasp for air in between sentences

[simonbaker]

Valuable animation, but could use some more explanation, such as: 1) under what conditions is the homologous dsDNA conveniently located nearby, and how is the physical coordination/matching of regions initiated; 2) other references (wikipedia) mention two different paths to resolving the bubble, one involving cross-over, the other not -- is this true, or is this video more accurate information showing only the non-crossover way; 3) how does the bubble know when it has synthesized enough new DNA on the invading strand to match the other hanging end of the broken DNA?

Why is the description of the video seemingly wrong ("Published on Aug 12, 2014
In this animation, we explore how a transposon moves as a consequence of DNA cut-and-paste transposition. ")?

[adrianbulfon]

One of the best videos Ive seen to date!

[roveradamus]

Good video. But the narration made me uncomfortable. Please record the audio away from the microphone please!

[sym]

even though you whispered through this whole thing this was a great visualization aid, thank you

[MrCharanthej]

Great videos on Homologous repair and Non homologous repair are

[Dornatum]

I don't understand how the C region is entirely newly synthesized DNA. I thought the endonucleases only removed one strand of DNA from the site of damage. At 0:36, I still see a single strand of C. How is that removed later on?

[karenn.]

good animation and well explained ! this was very helpful

[AMillionOs]

His voice makes you automatically think he knows what he's doing

[ImperialGoldfish]

Incredibly helpful explanation, thank you

[kufuffin]

Amazingly helpful animation. Thank you!

[xx]

brilliant video---!love the animation!

[DeemahAd]

Did you mention that the nuclease digests 5' ends???

[SrirachaPilsner]

why is werner herzog explaining homologous repair to me rn