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Thyroidectomy
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Thyroidectomy is recommended at different ages for patients with Multiple Endocrine Neoplasia type 2A (MEN2A) and type 2B (MEN2B) due to the high risk of medullary thyroid carcinoma (MTC):
- **MEN2A**: Thyroidectomy is generally recommended by age 5 or earlier if there are elevated calcitonin levels or if the specific RET mutation indicates a high risk.
- **MEN2B**: Thyroidectomy is recommended very early, usually within the first year of life, often before 6 months, because of the extremely high and early risk of aggressive MTC.
The timing of surgery is determined based on genetic testing, calcitonin levels, and family history.
- **MEN2A**: Thyroidectomy is generally recommended by age 5 or earlier if there are elevated calcitonin levels or if the specific RET mutation indicates a high risk.
- **MEN2B**: Thyroidectomy is recommended very early, usually within the first year of life, often before 6 months, because of the extremely high and early risk of aggressive MTC.
The timing of surgery is determined based on genetic testing, calcitonin levels, and family history.
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