CRISPR: Gene Editing in Fetal Therapy

CRISPR is a tool that’s been adapted to modify DNA. Researchers are studying it as a potential therapeutic for genetic conditions. Hear details about CRISPR gene editing and the collaborative research that’s underway at Children’s Hospital Colorado.

In this video, Medical Director of the Colorado Fetal Care Center at Children’s Colorado, Michael Zaretsky, MD, and Sean McGrath, PhD, from the University of Colorado Gates Center for Regenerative Medicine, discuss CRISPR gene editing. Dr. McGrath reviews what CRISPR is, how it works, its unique characteristics and associated safety concerns. Dr. Zaretsky discusses research that is being conducted at the Colorado Fetal Care Center in collaboration with researchers who are experts in the field. This research involves investigating the potential of CRISPR gene editing as a fetal therapy to correct mutations before delivery to improve outcomes for cystic fibrosis.

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