Updates in CAR T Cell Therapies

During this presentation of the Cancer Moonshot Seminar Series, Carl June, M.D. (University of Pennsylvania) discusses updates in chimeric antigen receptor (CAR) T cell therapies and his Immuno-Oncology Translational Network (IOTN) research. This work is related to the Blue Ribbon Panel recommendation to create an adult immunotherapy network.

[goldendelta]

For first time CAR-T cell patients is the transplant system first introduced in micro-increments to study cell integration sites, survival rates, and switch receptor effectiveness on attacking and multiplying before introducing higher amounts of CAR-T to reduce the chance of transplant failure? Also can CAR-T cell therapy be used as treatment for other cellular and viral diseases or auto-immune diseases?

[MrRomiBajwa]

Interesting but too many risk factors. Maybe I will to read the full study if it is available.

[test]

do we have approval for CAR-T therapy for NSCLC Lung Cancer ?

[brozbro]

It's a real medical short-coming that there is no realistic CAR T cell therapy information/discussion aimed at the cancer patient. I have just completed chemo/radiation for DLBCL and that treatment (I'm 75) was a true nightmare. My oncologist said, that if there is a relapse, CAR T might be the only avenue for me and the toxicity would be even worse. I have concluded that palliative/hospice will be my future, based on his statements. Unfortunately, there are no "What you can expect" videos other than a list of side-effects. Shame on you.

[vicentemamanipalomino]

por favor necesito para poblacion hispanohablante, gracias

[addapavan]

Is it useful for metastatic breast cancer (which spread to liver)?

[moorthi]

Its car t cell therapy Updates on gastric cancer or all solid tumor cancer cell Updates in this car t cell therapy