What is the Latest Research in Allergy and Asthma

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Latest Breakthroughs in Asthma and Allergy!


Did you know that is estimated to have more than 339 million people in the world that suffers from asthma? It is a public health problem in many countries regardless of the level of development. Most asthma related deaths occur in low and lower middle income countries.


Professor Christian Verkoff from #rostock University in #Germany believes that the most important recent finding has been a clinical study with an antibody against TSLP (activator of immunological processes) that is relevant for the pathogenesis of asthma.


From Asthma we focus then on Rhinitis which is one of the most common chronic diseases conditions. It is an IGE mediated disorder of the nose caused by the interaction airborne allergens with specific IGE type antibodies on the surface of mast cells. Over 400 million people around the world suffer from allergic rhinitis.


Dr. Lucas Van Oudenhove from #Leuven shared his latest research into allergic rhinitis which was accomplished alongside with Peter Hellings, Founder and Chair of EUFOREA, to study brain responses to nasal histamine provocation in a small group of allergic rhinitis patients and compare them to healthy controls.


📌 EUFOREA is an international non-profit organization forming an alliance of all stakeholders dedicated to reduce the prevalence and burden of allergies and airway diseases through the implementation of optimal patient care through education, research and advocacy.
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Clinical trial conducted at the Mater Hospital, Brisbane, Australia
Buteyko breathing techniques in asthma: a blinded randomised controlled trial.
Simon D Bowler, Amanda Green and Charles A Mitchell
- The study was carried out from January 1995 to April 1995.
- This study uses the gold standard of trials (blinded randomised controlled trial).
- The asthma patients were taught Buteyko the proper way, by actual Buteyko instructors.
- Quite a large group of asthma patients were taught.

Buteyko group:
Respiration after 3 months (l/min): 9, 6
Bronchodilators after 3 months: 96% less
Inhaled steroids after 3 months 49% less
Reduction of symptom scores after 3 months: 71%
After 6 weeks quality of life for the Buteyko group improved with 54% 

Control group:
Respiration after 3 months (l/min): 13, 3
Bronchodilators after 3 months: 7% less
Inhaled steroids after 3 months: remained the same
Reduction of symptom scores after 3 months: 14%

Additional results from the trial:
1: Asthma patients have lower CO2 values than the normal population
The study showed a big difference between end-tidal CO2 values of asthma patients and people without asthma: the normal group had an average end-tidal CO2 of 43 mmHg whereas the asthma patients had an average end-tidal Co2 of 34 mmHG. That's a big difference in CO2 levels which agrees with Professor Buteyko's claim that asthma is caused by low CO2 values.

2: Asthma patients breathe more than the normal population
Minute breathing volume was higher in asthma patients than in the group of normal people (without asthma). This agrees with Professor Buteyko claim that overbreathing (hyperventilation) causes asthma.

3: Asthma patients who practice Buteyko need less medication as they become better at Buteyko
The finding that the relative reduction in beta2-agonist medication was related to the proportionate reduction in minute volume with Buteyko is extremely meaningful. This really means that the more progress asthma patients make with Buteyko, the less medication they need. This is such an important finding that the title of the study could well have been: "Asthma patients who practice Buteyko Breathing need less medication as they become better at Buteyko"!

4: Buteyko does what it promises: change breathing habits and reduce disease symptoms
The finding that Buteyko lowers the average minute breathing volume from 14 liter/min to 9.6 liters/min proves that Buteyko Breathing really does significantly change breathing habits. The finding that asthma symptoms went down by 71% proves that Buteyko does improve health and reduces chronic disease symptoms. So these two finding combined together in effect prove that Buteyko Breathing does do what it promises.

5: Buteyko reverts hyperventilation
The finding that Buteyko lowers the average minute breathing volume from 14 liter/min to 9.6 liters/min is also a highly significant finding for people suffering from hyperventilation. Those suffering from hyperventilation can learn and practice Buteyko Breathing to reverse and improve their hyperventilation symptoms.

The Buteyko group experienced a significant reduction in the need for reliever medication and steroids, along with a greater improvement in quality of life. 
If an "Asthma Pill" came on the market today that would achieve such results, it would be prescribed to all asthmatics tomorrow.

On a side note:

“The control group showed little change in medication and quality of life despite being taught the conventional breathing exercises (relaxation techniques and abdominal breathing exercises which did not involve hypoventilation) that continue to be the mainstay of treatment in hospitals and clinics. It is interesting to note that half the control group was later taught the Buteyko breathing exercises (exercises in which subjects reduced the depth and frequency of respiration) and the results from this group were consistent with earlier findings.”

References:
Buteyko breathing techniques in asthma: a blinded randomised controlled trial. (1998)  Published: Medical Journal of Australia, 1998 Dec 7-21;169(11-12):575-8. By: Bowler SD, Green A, Mitchell CA.

Self-Management of Asthma Through Normalisation of Breathing - The Role of Breathing Therapy by Tess Graham, Physiotherapist, Practitioner of the Buteyko Method

Article Review "Buteyko breathing techniques in asthma: a blinded randomised controlled trial" by drs. Eduard Reuvers, 2017.

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